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Development of a simple disposable six minibioreactor system for suspension mammalian cell culture

Autor
Soley, A.; Fontova, A.; Gálvez, J.; Sarró, E.; Lecina, M.; Bragos, R.; Cairó, J.J.; Gòdia Casablancas, Francesc
Tipus d'activitat
Article en revista
Revista
Process biochemistry
Data de publicació
2012-04
Volum
47
Número
4
Pàgina inicial
597
Pàgina final
605
DOI
https://doi.org/10.1016/j.procbio.2011.12.022 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/16631 Obrir en finestra nova
Resum
A simple disposable six minibioreactor system has been developed in order to perform multiple cell culture experiments in parallel, as a tool to accelerate experimentation in cell culture optimization. The system consists of a fixed part containing all instrumentation, sensors and actuators, and a disposable part, a compact unit with six minibioreactors with 10–15 mL of working volume each. This single-use unit is made of transparent biocompatible plastic material (polystyrene). Each one of th...
Citació
Soley, A. [et al.]. Development of a simple disposable six minibioreactor system for suspension mammalian cell culture. "Process biochemistry", Abril 2012, vol. 47, núm. 4, p. 597-605.
Paraules clau
Cellular Activity, Cellular Concentration, Hexascreen, Mammalian Cell Culture, Miniaturized Bioreactors, On-line Monitoring, Oxygen Uptake Rate (our), Single-use
Grup de recerca
CREB - Centre de Recerca en Enginyeria Biomedica
IEB - Instrumentació Electrònica i Biomèdica

Participants

  • Soley, A.  (autor)
  • Fontova, A.  (autor)
  • Gálvez, Jordi  (autor)
  • Sarró Casanovas, Enric  (autor)
  • Lecina, Martí  (autor)
  • Bragos Bardia, Ramon  (autor)
  • Cairó Badillo, Jordi Joan  (autor)
  • Gòdia Casablancas, Francesc  (autor)