The thermal expansion of tienoxolol has been
investigated by X-ray powder diffraction up to its melting
temperature. The data indicate that the expansion is
anisotropic and even negative in one direction of the unit
cell. The supramolecular structure formed by hydrogenbonds
reflects that of a trellis, which explains the observed
behavior of tienoxolol crystals.
Nicolaï, B. [et al.]. Uniaxial negative thermal expansion in crystals of tienoxolol. "Structural chemistry", 17 Juny 2012, vol. 24, p. 279-283.