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Improving immunosensor performance through oriented immobilization of antibodies on carbon nanotube composite surfaces

Autor
Puertas, S.; de Gracia, M.; Mendoza, E.; Jiménez, C.; de la Fuente, J.; Fernández-Sánchez, C.; Grazú, V.
Tipus d'activitat
Article en revista
Revista
Biosensors and bioelectronics
Data de publicació
2013-05-05
Volum
43
Número
1
Pàgina inicial
1
Pàgina final
7
DOI
https://doi.org/10.1016/j.bios.2012.12.010 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/19980 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S0956566312008627 Obrir en finestra nova
Resum
We report the straightforward oriented covalent attachment of antibodies (Abs) on the surface of carboxylated multiwalled carbon nanotube-polystyrene (MWCNT-PS) materials. The combination of this composite material, applied as a robust electrochemical transducer platform, and its covalent functionalization with Abs in a controlled way by means of a two-step process, could contribute to the development of highly sensitive immunosensor devices. Using the simple and versatile carbodiimide chemistry...
Citació
Puertas, S. [et al.]. Improving immunosensor performance through oriented immobilization of antibodies on carbon nanotube composite surfaces. "Biosensors and bioelectronics", 05 Maig 2013, vol. 43, núm. 1, p. 1-7.
Paraules clau
Antibody, Carbodiimide chemistry, Carbon nanotubes, Immunoelectrochemical sensor, Oriented immobilization

Participants

  • Puertas, Sara  (autor)
  • de Gracia Villa, Maria  (autor)
  • Mendoza Gomez, Ernesto  (autor)
  • Jiménez Jorquera, Cecilia  (autor)
  • de la Fuente, Jesús M.  (autor)
  • Fernández Sánchez, César  (autor)
  • Grazú, Valeria  (autor)