Carregant...
Carregant...

Vés al contingut (premeu Retorn)

G protein-coupled receptor heterodimerization in the brain

Autor
Borroto, D.; Romero, W.; Garriga, P.; Ciruela, F.; Narvaez, M.; Tarakanov, O.; Palkovits, M.; Agnati, L.F.; Fuxe, K.
Tipus d'activitat
Article en revista
Revista
Methods in enzymology
Data de publicació
2013
Volum
521
Pàgina inicial
281
Pàgina final
294
DOI
https://doi.org/10.1016/B978-0-12-391862-8.00015-6 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/21956 Obrir en finestra nova
Resum
G protein-coupled receptors (GPCRs) play critical roles in cellular processes and signaling and have been shown to form heteromers with diverge biochemical and/or pharmacological activities that are different from those of the corresponding monomers or homomers. However, despite extensive experimental results supporting the formation of GPCR heteromers in heterologous systems, the existence of such receptor heterocomplexes in the brain remains largely unknown, mostly because of the lack of appro...
Citació
Borroto, D. [et al.]. G protein-coupled receptor heterodimerization in the brain. "Methods in enzymology", 2013, vol. 521, p. 281-294.
Paraules clau
Allosteric Modulation, Depression, Fibroblast Growth Factor Receptor, Neuronal Plasticity, Receptor Heterocomplex, Serotonin Receptors
Grup de recerca
CEBIM - Centre de Biotecnologia Molecular
GBMI - Grup de Biotecnologia Molecular i Industrial

Participants

  • Borroto Escuela, Dasiel Óscar  (autor)
  • Romero Fernández, Wilber  (autor)
  • Garriga Sole, Pere  (autor)
  • Ciruela, Francisco  (autor)
  • Narvaez, Manuel  (autor)
  • Tarakanov, O.V.  (autor)
  • Palkovits, Miklós  (autor)
  • Agnati, Luigi F.  (autor)
  • Fuxe, Kjell  (autor)