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Examining the formation of specific interactions between poly(3,4-ethylenedioxythiophene) and nucleotide bases

Autor
Zanuy, D.; Teixeira-Dias, Bruno; del Valle, LJ.; Poater, J.; Solà, M.; Aleman, C.
Tipus d'activitat
Article en revista
Revista
RSC advances
Data de publicació
2012-12-17
Volum
3
Número
8
Pàgina inicial
2639
Pàgina final
2649
DOI
https://doi.org/10.1039/c2ra22640e Obrir en finestra nova
URL
http://pubs.rsc.org/en/Content/ArticleLanding/2013/RA/c2ra22640e#!divAbstract Obrir en finestra nova
Resum
he formation of specific interaction between poly(3,4-ethylenedioxythiophene) (PEDOT) and adenine (A), cytosine (C) and thymine (T) single stranded homonucleotides has been investigated, complementing our previous investigation on complexes formed by PEDOT and guanine (G) homonucleotide (B. Teixeira-Dias et al, Soft Matter, 2011, 7, 9922–9932). Results derived from UV-vis and FTIR spectroscopy suggest that A and, especially, C homonucleotides form adducts dominated by non-specific electrostati...
Paraules clau
4-ethylenedioxythiophene, Experimental observation, FTIR spectroscopy, Guanine, Molecular dynamics simulations, Nucleotide basis, Poly-3, Soft matter, Specific interaction
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies
PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.

Participants