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Absolute quantification in dopaminergic neurotransmission SPET imaging using a Monte Carlo-based scatter correction and fully 3D reconstruction

Autor
Cot, A.; Falcón, C.; Crespo, C.; Sempau, J.; Pareto, D.; Bullich, S.; Lomeña, F.; Calviño, F.; Pavía, J.; Ros, D.
Tipus d'activitat
Article en revista
Revista
Journal of nuclear medicine
Data de publicació
2005-09
Volum
46
Número
9
Pàgina inicial
1497
Pàgina final
1504
Repositori
http://hdl.handle.net/2117/11211 Obrir en finestra nova
URL
http://jnm.snmjournals.org/cgi/reprint/46/9/1497.pdf Obrir en finestra nova
Resum
Dopamine transporter (DAT) ligands have been developed for in vivo imaging of the dopaminergic system in SPECT. Although the visual analysis of SPECT images is, in general, suitable for clinical assessment, the accurate quantification of the striatal uptake might increase the sensitivity of the technique and help in the early diagnosis, follow-up, and eventual treatment response of Parkinson’s disease (PD). This work is focused on assessment of the quantification of specific uptake of 99mTc- D...
Citació
Cot, A. [et al.]. Absolute quantification in dopaminergic neurotransmission SPET imaging using a Monte Carlo-based scatter correction and fully 3D reconstruction. "Journal of nuclear medicine", Setembre 2005, vol. 46, núm. 9, p. 1497-1504.
Grup de recerca
ANT - Advanced Nuclear Technologies Research Group
CREB - Centre de Recerca en Enginyeria Biomedica
DRM - Dosimetria i Radiofísica Mèdica

Participants

  • Cot, A  (autor)
  • Falcón, C  (autor)
  • Crespo, C  (autor)
  • Sempau Roma, Josep  (autor)
  • Pareto, Deborah  (autor)
  • Bullich, S  (autor)
  • Lomeña, F  (autor)
  • Calviño Tavares, Francisco  (autor)
  • Pavía, J  (autor)
  • Ros, D  (autor)