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Calcium phosphate cements loaded with basic fibroblast growth factor: Delivery and in vitro cell response

Autor
Perez, R.; Kim, T.H; Kim, M.; Jang, JH; Ginebra, M.P.; Kim, H-W.
Tipus d'activitat
Article en revista
Revista
Journal of biomedical materials research. Part A
Data de publicació
2013-04
Volum
101A
Número
4
Pàgina inicial
923
Pàgina final
931
DOI
https://doi.org/10.1002/jbm.a.34390 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/19763 Obrir en finestra nova
Resum
Combining calcium phosphate cements (CPCs) with bioactive molecules improves their bone regeneration potential. Although CPCs are highly osteoconductive, sometimes they have limited biological responses, especially in terms of cell proliferation. Here, we used basic fibroblast growth factor (bFGF) in an -tricalcium phosphate cement with different initial powder sizes (coarse vs. fine; designated as CPC-C and CPC-F, respectively) and investigated the behavior of bFGF loading and release, as well ...
Citació
Perez, R.A. [et al.]. Calcium phosphate cements loaded with basic fibroblast growth factor: Delivery and in vitro cell response. "Journal of biomedical materials research. Part A", Abril 2013, vol. 101A, núm. 4, p. 923-931.
Paraules clau
bone regeneration, calcium phosphate cements, cell proliferation, growth factor delivery, powder size
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants