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Quantification of dopaminergic neurotransmission SPECT studies with I-123-labelled radioligands. A comparison between different imaging systems and data acquisition protocols using Monte Carlo simulation

Autor
Crespo, C.; Gallego, J.; Cot, A.; Falcon, C.; Bullich, S.; Pareto, D.; Aguiar, P.; Sempau, J.; Lomena, F.; Calviño, F.; Pavia, J.; Ros, D.
Tipus d'activitat
Article en revista
Revista
European journal of nuclear medicine and molecular Imaging
Data de publicació
2008-07
Volum
35
Número
7
Pàgina inicial
1334
Pàgina final
1342
DOI
https://doi.org/10.1007/s00259-007-0711-z Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/11209 Obrir en finestra nova
Resum
Purpose 123I-labelled radioligands are commonly used for single-photon emission computed tomography (SPECT) imaging of the dopaminergic system to study the dopamine transporter binding. The aim of this work was to compare the quantitative capabilities of two different SPECT systems through Monte Carlo (MC) simulation. Methods The SimSET MC code was employed to generate simulated projections of a numerical phantom for two gamma cameras equipped with a parallel and a fan-beam collimator, respectiv...
Citació
Crespo, C. [et al.]. Quantification of dopaminergic neurotransmission SPECT studies with I-123-labelled radioligands. A comparison between different imaging systems and data acquisition protocols using Monte Carlo simulation. "European journal of nuclear medicine and molecular Imaging", Juliol 2008, vol. 35, núm. 7, p. 1334-1342.
Grup de recerca
ANT - Advanced Nuclear Technologies Research Group
CREB - Centre de Recerca en Enginyeria Biomedica
DRM - Dosimetria i Radiofísica Mèdica

Participants

  • Crespo, C  (autor)
  • Gallego, J  (autor)
  • Cot, A  (autor)
  • Falcon, C  (autor)
  • Bullich, S  (autor)
  • Pareto, Deborah  (autor)
  • Aguiar, P  (autor)
  • Sempau Roma, Josep  (autor)
  • Lomena, F  (autor)
  • Calviño Tavares, Francisco  (autor)
  • Pavia, J  (autor)
  • Ros, D  (autor)