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Spatial orientation of collagen fibers in the abdominal aortic aneurysm's wall and its relation to wall mechanics

Autor
Gasser, T.; Gallinetti, S.; Xing, X.; Forsell, C.; Swedenborg, J.; Roy, J.
Tipus d'activitat
Article en revista
Revista
Acta biomaterialia
Data de publicació
2012-08
Volum
8
Número
8
Pàgina inicial
3091
Pàgina final
3103
DOI
https://doi.org/10.1016/j.actbio.2012.04.044 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/19654 Obrir en finestra nova
Resum
Collagen is the most abundant protein in mammals and provides the abdominal aortic aneurysm (AAA) wall with mechanical strength, stiffness and toughness. Specifically, the spatial orientation of collagen fibers in the wall has a major impact on its mechanical properties. Apart from valuable microhistological information, this data can be integrated by histomechanical constitutive models thought to improve biomechanical simulations, i.e. to improve the biomechanical rupture risk assessment of AAA...
Citació
Gasser, T. [et al.]. Spatial orientation of collagen fibers in the abdominal aortic aneurysm's wall and its relation to wall mechanics. "Acta biomaterialia", Agost 2012, vol. 8, núm. 8, p. 3091-3103.
Paraules clau
AAA wall, Collagen formation, Constitutive modeling, Microhistology, Polarized light microscopy

Participants

  • Gasser, Thomas Christian  (autor)
  • Gallinetti, Sara  (autor)
  • Xing, Xiao  (autor)
  • Forsell, Carolina  (autor)
  • Swedenborg, Jesper A.  (autor)
  • Roy, Joy W.  (autor)