Carregant...
Carregant...

Vés al contingut (premeu Retorn)

Solid-state properties and dehydration behavior of the active pharmaceutical ingredient potassium guaiacol-4-sulfonate

Autor
Mahé, N.; Nicolaï, B.; Del Barrio, M.; Perrin, M.; Do, B.; Tamarit, J. Ll.; Céolin, R.; Rietveld, I.
Tipus d'activitat
Article en revista
Revista
Crystal growth and design
Data de publicació
2013-05-20
Volum
13
Número
7
Pàgina inicial
3028
Pàgina final
3035
DOI
https://doi.org/10.1021/cg400427v Obrir en finestra nova
Projecte finançador
Dinámica en sólidos desordenados
TRANSICIONS DE FASES, POLIMORFISME I DINÀMICA DE LA METAESTABILITAT
Repositori
http://hdl.handle.net/2117/20757 Obrir en finestra nova
URL
http://pubs.acs.org/doi/abs/10.1021/cg400427v Obrir en finestra nova
Resum
Potassium guaiacolsulfonate is an active pharmaceutical ingredient that has been in use for more than a century, and it is still widely used in cough syrups. Nonetheless, no crystal structure has ever been determined to facilitate quality control. This is all the more surprising because two isomers are known to exist. A commercial sample has been studied by X-ray diffraction and thermogravimetric methods. It consists of potassium guaiacol-4-sulfonate, and it crystallizes in the monoclinic space ...
Citació
Mahé, N. [et al.]. Solid-state properties and dehydration behavior of the active pharmaceutical ingredient potassium guaiacol-4-sulfonate. "Crystal growth and design", 20 Maig 2013, vol. 13, núm. 7, p. 3028-3035.
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
GCM - Grup de Caracterització de Materials

Participants

  • Mahé, Nathalie  (autor)
  • Nicolaï, Béatrice  (autor)
  • Del Barrio Casado, Maria  (autor)
  • Perrin, Marc Antoine  (autor)
  • Do, Bernard  (autor)
  • Tamarit Mur, Jose Luis  (autor)
  • Céolin, René  (autor)
  • Rietveld, Ivo B.  (autor)