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A bioactive elastin-like recombinamer reduces unspecific protein adsorption and enhances cell response on titanium surfaces.

Autor
Salvagni, E.; Berguig, G.; Engel, E.; Rodriguez-Cabello , J.C.; Coullerez, G.; Textor, M.; Planell, J. A.; Gil, F.J.; Aparicio, C.
Tipus d'activitat
Article en revista
Revista
Colloids and Surfaces B. Biointerfaces
Data de publicació
2014-02-01
Volum
17
Pàgina inicial
225
Pàgina final
233
DOI
https://doi.org/10.1016/j.colsurfb.2013.10.008 Obrir en finestra nova
Projecte finançador
A Systems Approach to Tissue Engineering Processes and Products
Repositori
http://hdl.handle.net/2117/20907 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S092777651300636X Obrir en finestra nova
Resum
We present the immobilization on synthetic substrates of elastin-like recombinamers (ELR) that combine a bioactive motif for cell adhesion with protein antifouling properties. Physical adsorption of the recombinamers and covalent-grafting through organosilane chemistry were investigated. The biochemically-modified surfaces were thoroughly characterized and tested for protein absorption in serum by fluorescence-labelling, XPS, Ellipsometry, and OWLS. The ELR were successfully grafted and stable, ...
Citació
Salvagni, E. [et al.]. A bioactive elastin-like recombinamer reduces unspecific protein adsorption and enhances cell response on titanium surfaces.. "Colloids and Surfaces B. Biointerfaces", 17 Octubre 2013, vol. 17, núm. 114C, p. 225-233.
Paraules clau
Bioactivity, Biofunctionalization, Biomimetic, Cell response, Protein immobilization, Protein resistance
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants