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Stuck with the right choice: avß3- or a5ß1-selective integrin ligands were functionalized for surface coating without losing activity and selectivity. The coating of nanostructured gold surfaces with these compounds stimulated subtype-selective cell adhesion of genetically modified avß3- or a5ß1-expressing fibroblasts in vitro.
Rechenmacher, F. [et al.]. Functionalizing avß3- or a5ß1-selective integrin antagonists for surface coating: A new tool to discriminate integrin subtypes in vitro. "Angewandte chemie. International edition", 2013, vol. 52, núm. 5, p. 1572-1575.