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Functionalizing avß3- or a5ß1-selective integrin antagonists for surface coating: A new tool to discriminate integrin subtypes in vitro

Autor
Rechenmacher, F.; Neubauer, S.; Polleux, J.; Mas-Moruno, C.; De Simone, M.; Cavalcanti-Adam, E.; Spatz, J.; Fässler, R.; Kessler, H.
Tipus d'activitat
Article en revista
Revista
Angewandte chemie. International edition
Data de publicació
2013
Volum
52
Número
5
Pàgina inicial
1572
Pàgina final
1575
DOI
https://doi.org/10.1002/anie.201206370 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/22774 Obrir en finestra nova
URL
http://onlinelibrary.wiley.com/doi/10.1002/anie.201206370/abstract Obrir en finestra nova
Resum
Thumbnail image of graphical abstract Stuck with the right choice: avß3- or a5ß1-selective integrin ligands were functionalized for surface coating without losing activity and selectivity. The coating of nanostructured gold surfaces with these compounds stimulated subtype-selective cell adhesion of genetically modified avß3- or a5ß1-expressing fibroblasts in vitro.
Citació
Rechenmacher, F. [et al.]. Functionalizing avß3- or a5ß1-selective integrin antagonists for surface coating: A new tool to discriminate integrin subtypes in vitro. "Angewandte chemie. International edition", 2013, vol. 52, núm. 5, p. 1572-1575.
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants

  • Rechenmacher, Florian  (autor)
  • Neubauer, Stefanie  (autor)
  • Polleux, Julien  (autor)
  • Mas Moruno, Carlos  (autor)
  • De Simone, Mariarosaria  (autor)
  • Cavalcanti-Adam, Elisabetta Ada  (autor)
  • Spatz, Joachim P.  (autor)
  • Fässler, Reinhard  (autor)
  • Kessler, Horst  (autor)