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On the polymorphism of l -citrulline: Crystal structure and characterization of the orthorhombic d form

Autor
Allouchi, H.; Nicolaï, B.; Del Barrio, M.; Céolin, R.; Mahé, N.; Tamarit, J. Ll.; Do, B.; Rietveld, I.
Tipus d'activitat
Article en revista
Revista
Crystal growth and design
Data de publicació
2014-03-01
Volum
14
Número
3
Pàgina inicial
1279
Pàgina final
1286
DOI
https://doi.org/10.1021/cg401801u Obrir en finestra nova
Projecte finançador
Dinámica en sólidos desordenados
Repositori
http://hdl.handle.net/2117/23302 Obrir en finestra nova
Resum
Solid-state properties of active pharmaceutical compounds are closely related to their dissolution behavior and bioavailability, and understanding their phase behavior leads to better control in the drug formulation process. L-Citrulline is an amino acid, which is known to exhibit polymorphism; however, only the structure of the alpha form is reported in the literature. The structure of the form has been elusive due to lack of good quality single crystals. It has been found to be orthorhombic P2...
Citació
Allouchi, H. [et al.]. On the polymorphism of l -citrulline: Crystal structure and characterization of the orthorhombic d form. "Crystal growth and design", 01 Març 2014, vol. 14, núm. 3, p. 1279-1286.
Paraules clau
Acid, Hydrochloride
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
GCM - Grup de Caracterització de Materials

Participants