Carregant...
Carregant...

Vés al contingut (premeu Retorn)

Apathy in parkinson's disease: Neurophysiological evidence of impaired incentive processing

Autor
Martinez, S.; Riba, J.; Fernandez, R.; Pagonabarraga, J.; Pascual, B.; Antonijoan, R.; Romero, S.; Mañanas, M.A.; Garcia, C.; Kulisevsky, J.
Tipus d'activitat
Article en revista
Revista
Journal of neuroscience
Data de publicació
2014
Volum
34
Número
17
Pàgina inicial
5918
Pàgina final
5926
DOI
https://doi.org/10.1523/JNEUROSCI.0251-14.2014 Obrir en finestra nova
URL
http://www.jneurosci.org/content/34/17/5918 Obrir en finestra nova
Resum
Apathy is one of the most common and debilitating nonmotor manifestations of Parkinson's disease (PD) and is characterized by diminished motivation, decreased goal-directed behavior, and flattened affect. Despite its high prevalence, its underlying mechanisms are still poorly understood, having been associated with executive dysfunction, and impaired emotional processing and decision making. Apathy, as a syndrome, has recently been associated with reduced activation in the ventral striatum, sugg...
Paraules clau
Apathy, Feedback-related Negativity, Incentive Processing, Parkinson's Disease
Grup de recerca
BIOART - Anàlisi de Biosenyals per a la Rehabilitació i la Teràpia
CREB - Centre de Recerca en Enginyeria Biomedica

Participants

  • Martinez Horta, Saul  (autor)
  • Riba Serrano, Jordi  (autor)
  • Fernandez De Bobadilla, Ramon  (autor)
  • Pagonabarraga, Javier  (autor)
  • Pascual Sedano, Berta  (autor)
  • Antonijoan, Rosa Maria  (autor)
  • Romero Lafuente, Sergio  (autor)
  • Mañanas Villanueva, Miguel Angel  (autor)
  • Garcia Sanchez, Carmen  (autor)
  • Kulisevsky, Jaime J.  (autor)