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ReLA, a local alignment search tool for the identification of distal and proximal gene regulatory regions and their conserved transcription factor binding sites

Autor
González, S.; Montserrat-Sentís, B.; Sanchez, F.; Puiggros, M.; Blanco, E.; Alex Ramirez; Torrents , D.
Tipus d'activitat
Article en revista
Revista
Bioinformatics
Data de publicació
2012-03
Volum
28
Número
6
Pàgina inicial
763
Pàgina final
770
DOI
https://doi.org/10.1093/bioinformatics/bts024 Obrir en finestra nova
URL
http://bioinformatics.oxfordjournals.org/content/early/2012/01/16/bioinformatics.bts024 Obrir en finestra nova
Resum
Motivation: The prediction and annotation of the genomic regions involved in gene expression has been largely explored. Most of the energy has been devoted to the development of approaches that detect transcription start sites (TSS), leaving the identification of regulatory regions and their functional transcription factor binding sites (TFBSs) largely unexplored and with important quantitative and qualitative methodological gaps. Results: We have developed ReLA (for REgulatory region Local Ali...
Grup de recerca
CAP - Grup de Computació d'Altes Prestacions

Participants

  • González, Santiago  (autor)
  • Montserrat Sentís, Bàrbara  (autor)
  • Sanchez Castaño, Friman  (autor)
  • Puiggros, Montserrat  (autor)
  • Blanco Garcia, Enrique  (autor)
  • Ramirez Bellido, Alejandro  (autor)
  • Torrents Rodas, David  (autor)