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A hazard ratio was estimated by a ratio of median survival times, but with considerable uncertainty

Autor
Cortes, J.; Gonzalez, J.; Campbell , M.J.; Cobo, E.
Tipus d'activitat
Article en revista
Revista
Journal of clinical epidemiology
Data de publicació
2014-10-01
Volum
67
Número
1
Pàgina inicial
1172
Pàgina final
1177
DOI
https://doi.org/10.1016/j.jclinepi.2014.05.017 Obrir en finestra nova
URL
http://www.jclinepi.com/article/S0895-4356%2814%2900227-3/abstract Obrir en finestra nova
Resum
Objectives: To evaluate the empirical concordance between the hazard ratio (HR) and the median ratio (MR) in survival cancer studies. Study Design and Setting: We selected all cancer survival articles from the New England Journal of Medicine published between 2000 and 2010. The qualitative concordance was estimated by the proportion of measured pairs in which the treatment effects for the MR and HR are in the same direction. The quantitative concordance was assessed through (1) the mean differen...
Paraules clau
Cancer, Clinical trial, Concordance, Hazard ratio, Median ratio, Survival
Grup de recerca
GNOM - Grup d'Optimització Numèrica i Modelització
GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica

Participants