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DNA adsorbed on hydroxyapatite surfaces

Autor
del Valle, LJ.; Bertran, O.; Chaves, G.; Revilla-López, G.; Rivas, M.; Casanovas, J.; Turon, P.; Puiggali, J.; Aleman, C.; Casas, M.T.
Tipus d'activitat
Article en revista
Revista
Journal of materials chemistry B
Data de publicació
2014-01-01
Volum
2
Número
40
Pàgina inicial
6953
Pàgina final
6966
DOI
https://doi.org/10.1039/c4tb01184h Obrir en finestra nova
Projecte finançador
Nuevos polímeros derivados de lactida: estructura, aplicaciones biomédicas y microprocesado.
POLIMEROS CONDUCTORES Y SUS DERIVADOS HIBRIDOS CON APLICACIONES AVANZADAS
Repositori
http://hdl.handle.net/2117/24728 Obrir en finestra nova
URL
http://pubs.rsc.org/en/content/articlepdf/2014/tb/c4tb01184h Obrir en finestra nova
Resum
Hydroxyapatite (HAp) particles with very different surface charges and compositions (i.e. different Ca/P and CO32-/PO43- ratios) have been obtained by varying the experimental conditions used during the chemical precipitation process. The DNA adsorption capacity and protection imparted against the attack of nucleases of HAp particles have been proved to depend on the surface charge while the buffering capacity is affected by the chemical composition. On the basis of both the surface charge and t...
Citació
del Valle, LJ. [et al.]. DNA adsorbed on hydroxyapatite surfaces. "Journal of materials chemistry B", 01 Gener 2014, vol. 2, núm. 40, p. 6953-6966.
Paraules clau
BETA-TRICALCIUM PHOSPHATE, BINDING, BIOMATERIALS, FORCE-FIELD, GENE DELIVERY, MINERALIZATION, MOLECULAR-DYNAMICS, NANOPARTICLES, NUCLEIC-ACIDS, X-RAY
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies
PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.

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