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Oscillation patterns in negative feedback loops

Autor
Pigolotti, S.; Krishna, S.; Jensen, Mogens H.
Tipus d'activitat
Article en revista
Revista
Proceedings of the National Academy of Sciences of the United States of America
Data de publicació
2007-04-05
Volum
104
Número
16
Pàgina inicial
6533
Pàgina final
6537
DOI
https://doi.org/10.1073/pnas.0610759104 Obrir en finestra nova
URL
http://www.pnas.org/content/104/16/6533.short Obrir en finestra nova
Resum
Organisms are equipped with regulatory systems that display a variety of dynamical behavior ranging from simple stable steady states, to switching and multistability, to oscillations. Earlier work has shown that oscillations in protein concentrations or gene expression levels are related to the presence of at least one negative feedback loop in the regulatory network. Here, we study the dynamics of a very general class of negative feedback loops. Our main result is that, when a single negative f...
Grup de recerca
DONLL - Dinàmica no Lineal, Òptica no Lineal i Làsers

Participants

  • Pigolotti, Simone  (autor)
  • Krishna, Sandeep  (autor)
  • Jensen, Mogens H.  (autor)