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Exploring Diallelic genetic markers: The Hardy Weinberg package

Autor
Graffelman, J.
Tipus d'activitat
Article en revista
Revista
Journal of statistical software
Data de publicació
2015-03
Volum
64
Número
3
Pàgina inicial
1
Pàgina final
23
Repositori
http://hdl.handle.net/2117/76647 Obrir en finestra nova
URL
http://www.jstatsoft.org/v64/i03 Obrir en finestra nova
Resum
Testing genetic markers for Hardy-Weinberg equilibrium is an important issue in genetic association studies. The HardyWeinberg package o ers the classical tests for equilibrium, functions for power computation and for the simulation of marker data under equilibrium and disequilibrium. Functions for testing equilibrium in the presence of missing data by using multiple imputation are provided. The package also supplies various graphical tools such as ternary plots with acceptance regions, log-rati...
Citació
Graffelman, J. Exploring Diallelic genetic markers: The Hardy Weinberg package. "Journal of statistical software", Març 2015, núm. 3, p. 1-23.
Paraules clau
Q-Q plot, chi-square test, exact test, log-ratio., permutation test, power, ternary plot
Grup de recerca
COSDA-UPC - COmpositional and Spatial Data Analysis

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