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Biocompatibility and drug release behavior of scaffolds prepared by coaxial electrospinning of poly(butylene succinate) and polyethylene glycol

Autor
Llorens, E.; Ibañez, H.; del Valle, LJ.; Puiggali, J.
Tipus d'activitat
Article en revista
Revista
Materials science and engineering C. Biomimetic and supramolecular systems
Data de publicació
2015-04-01
Volum
49
Pàgina inicial
472
Pàgina final
484
DOI
https://doi.org/10.1016/j.msec.2015.01.039 Obrir en finestra nova
Projecte finançador
Nuevos polímeros derivados de lactida: estructura, aplicaciones biomédicas y microprocesado.
Repositori
http://hdl.handle.net/2117/85886 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S0928493115000491 Obrir en finestra nova
Resum
Scaffolds constituted by electrospun microfibers of poly(ethylene glycol) (PEG) and poly(butylene succinate) (PBS) were studied. Specifically, coaxial microfibers having different core-shell distributions and compositions were considered as well as uniaxial micro/nanofibers prepared from mixtures of both polymers. Processing conditions were optimized for all geometries and compositions and resulting morphologies (i.e. diameter and surface texture) characterized by scanning electron microscopy. C...
Citació
Llorens, E., Ibañez, H., del Valle, LJ., Puiggali, J. Biocompatibility and drug release behavior of scaffolds prepared by coaxial electrospinning of poly(butylene succinate) and polyethylene glycol. "Materials science and engineering C. Biomimetic and supramolecular systems", 01 Abril 2015, vol. 49, p. 472-484.
Paraules clau
Coaxial electrospinning, Drug release, Poly(butylene succinate), Poly(ethylene glycol), Scaffolds, curcumin, delivery, fibers, mixtures, morphology, polylactide, polymer nanofibers, surfaces
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.

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