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Study on the use of 3-aminopropyltriethoxysilane and 3-chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti-Nb-Hf alloy

Autor
Paredes, V.; Salvagni, E.; Rodriguez, E.; Gil, F.J.; Manero, J.
Tipus d'activitat
Article en revista
Revista
Journal of biomedical materials research. Part B, Applied biomaterials
Data de publicació
2015-04-01
Volum
103
Número
3
Pàgina inicial
495
Pàgina final
502
DOI
https://doi.org/10.1002/jbm.b.33226 Obrir en finestra nova
Projecte finançador
SUPERFICIES METÁLICAS BIOFUNCIONALIZADAS PARA LA RECUPERACION DE TEJIDOS
Repositori
http://hdl.handle.net/2117/85948 Obrir en finestra nova
URL
http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33226/abstract Obrir en finestra nova
Resum
A biocompatible new titanium alloy Ti-16Hf-25Nb with low elastic modulus (45 GPa) and the use of short bioadhesive peptides derived from the extracellular matrix have been studied. In terms of cell adhesion, a comparative study with mixtures of short peptides as RGD (Arg-Gly-Asp)/PHSRN (Pro-His-Ser-Arg-Asn) and RGD (Arg-Gly-Asp)/FHRRIKA (Phe-His-Arg-Arg-Ile-Lys-Ala) have been carried out with rat mesenchymal cells. The effect of these mixtures of short peptides have already been studied but ther...
Citació
Paredes, V., Salvagni, E., Rodriguez, E., Gil, F.J., Manero, J. Study on the use of 3-aminopropyltriethoxysilane and 3-chloropropyltriethoxysilane to surface biochemical modification of a novel low elastic modulus Ti-Nb-Hf alloy. "Journal of biomedical materials research. Part B, Applied biomaterials", 01 Abril 2015, vol. 103, núm. 3, p. 495-502.
Paraules clau
APTES, CPTES, XPS, adhesion, attachment, biomimetic peptide surfaces, covalent immobilization, low elastic modulus alloys, monolayers, osteoblast-like cells, short peptides, silica
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

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