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Inflammatory response to nano- and microstructured hydroxyapatite

Autor
Mestres, G.; Español, M.; xia, W.; Persson, C.; Ginebra, M.P.; Karlsson, M.
Tipus d'activitat
Article en revista
Revista
PloS one
Data de publicació
2015-04-02
Volum
10
Número
4
DOI
https://doi.org/10.1371/journal.pone.0120381 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/84946 Obrir en finestra nova
URL
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120381 Obrir en finestra nova
Resum
The proliferation and activation of leukocytes upon contact with a biomaterial play a crucial role in the degree of inflammatory response, which may then determine the clinical failure or success of an implanted biomaterial. The aim of this study was to evaluate whether nano-and microstructured biomimetic hydroxyapatite substrates can influence the growth and activation of macrophage-like cells. Hydroxyapatite substrates with different crystal morphologies consisting of an entangled network of p...
Citació
Mestres, G., Español, M., xia, W., Persson, C., Ginebra, M.P., Karlsson, M. Inflammatory response to nano- and microstructured hydroxyapatite. "PLoS one", 02 Abril 2015, vol. 10, núm. 4.
Paraules clau
Calcium-phosphate cement, activation, biomaterials, bone-marrow, cell response, in-vitro, macrophages, particle-size, topography, tricalcium phosphate
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants

Arxius