Carregant...
Carregant...

Vés al contingut (premeu Retorn)

Mimicking bone extracellular matrix: Integrin-binding peptidomimetics enhance osteoblast-like cells adhesion, proliferation, and differentiation on titanium

Autor
Fraioli, R.; Rechenmacher, F.; Neubauer, S.; Manero, J.; Gil, F.J.; Kessler, H.; Mas-Moruno, C.
Tipus d'activitat
Article en revista
Revista
Colloids and Surfaces B. Biointerfaces
Data de publicació
2015-04-01
Volum
128
Pàgina inicial
191
Pàgina final
200
DOI
https://doi.org/10.1016/j.colsurfb.2014.12.057 Obrir en finestra nova
Projecte finançador
Grup de Recerca Consolidat de la Generalitat de Catalunya
Grup de recerca consolidat de la generalitat de catalunya
NUEVOS BIOMATERIALES METALICOS BIOFUNCIONALIZADOS PARA APLICACIONES ORTOPEDICAS,
Repositori
http://hdl.handle.net/2117/89018 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S0927776515000168 Obrir en finestra nova
Resum
Interaction between the surface of implants and biological tissues is a key aspect of biomaterials research. Apart from fulfilling the non-toxicity and structural requirements, synthetic materials are asked to direct cell response, offering engineered cues that provide specific instructions to cells. This work explores the functionalization of titanium with integrin-binding peptidomimetics as a novel and powerful strategy to improve the adhesion, proliferation and differentiation of osteoblast-l...
Citació
Fraioli, R., Rechenmacher, F., Neubauer, S., Manero, J., Gil, F.J., Kessler, H., Mas-Moruno, C. Mimicking bone extracellular matrix: Integrin-binding peptidomimetics enhance osteoblast-like cells adhesion, proliferation, and differentiation on titanium. "Colloids and Surfaces B. Biointerfaces", 01 Abril 2015, vol. 128, p. 191-200.
Paraules clau
Functionalization, Integrins, Osteointegration, Peptidomimetics, Titanium, alpha-v-beta-3, behavior, biomaterials, cyclic rgd peptides, fibronectin, implant materials, osteogenic differentiation, saos-2 cells, specificity, surface-chemistry
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants