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Evaluation of multiple comparison correction procedures in drug assessment studies using LORETA maps

Autor
Alonso, J.F.; Romero, S.; Mañanas, M.A.; Rojas, M.; Riba, J.; Barbanoj, M.J.
Tipus d'activitat
Article en revista
Revista
Medical and biological engineering and computing
Data de publicació
2015-10-01
Volum
53
Número
10
Pàgina inicial
1011
Pàgina final
1023
DOI
https://doi.org/10.1007/s11517-015-1315-6 Obrir en finestra nova
Projecte finançador
Sistemas multicanal de análisis y sensorización no invasiva para la rehabilitación y monitorización clínica
Repositori
http://hdl.handle.net/2117/85186 Obrir en finestra nova
URL
http://link.springer.com/article/10.1007%2Fs11517-015-1315-6 Obrir en finestra nova
Resum
The identification of the brain regions involved in the neuropharmacological action is a potential procedure for drug development. These regions are commonly determined by the voxels showing significant statistical differences after comparing placebo-induced effects with drug-elicited effects. LORETA is an electroencephalography (EEG) source imaging technique frequently used to identify brain structures affected by the drug. The aim of the present study was to evaluate different methods for the ...
Citació
Alonso, J.F., Romero, S., Mañanas, M.A., Rojas, M., Riba, J., Barbanoj, M.J. Evaluation of multiple comparison correction procedures in drug assessment studies using LORETA maps. "Medical and biological engineering and computing", 01 Octubre 2015, vol. 53, núm. 10, p. 1011-1023.
Paraules clau
Eeg Tomography, Loreta, Multiple Testing, Nonparametric Permutation Test, Cluster Mass, Alprazolam, Resolution Electromagnetic Tomography, Brain Electrical-activity, False Discovery Rate, Double-blind, Alzheimers-disease, Pharmacodynamics, Permutation, Buspirone, Tests, Voxel
Grup de recerca
BIOART - Anàlisi de Biosenyals per a la Rehabilitació i la Teràpia
CREB - Centre de Recerca en Enginyeria Biomedica

Participants