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A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials

Autor
de Sola, S.; De la Torre, R.; Sánchez Benavides, G.; Benejam, B.; Cuenca, A.; del Hoyo, L.; Rodríguez, J.; Catuara-Solarz, S.; Sánchez-Gutiérrez, J.; Dueñas-Espín, I.; Hernández, G.; Peña-Casanovas, J.; Langohr, K.; Videla, S.; Blehaut, H.; Farré, M.; Dierssen, M.
Tipus d'activitat
Article en revista
Revista
Frontiers in Psychology
Data de publicació
2015-06-04
Volum
6
Pàgina inicial
1
Pàgina final
14
DOI
10.3389/fpsyg.2015.00708
Repositori
http://hdl.handle.net/2117/78506 Obrir en finestra nova
URL
http://journal.frontiersin.org/article/10.3389/fpsyg.2015.00708/full Obrir en finestra nova
Resum
The recent prospect of pharmaceutical interventions for cognitive impairment of Down syndrome (DS) has boosted a number of clinical trials in this population. However, running the trials has raised some methodological challenges and questioned the prevailing methodology used to evaluate cognitive functioning of DS individuals. This is usually achieved by comparing DS individuals to matched healthy controls of the same mental age. We propose a new tool, the TESDAD Battery that uses comparison wit...
Citació
de Sola, S., De la Torre, R., Sánchez Benavides, G., Benejam, B., Cuenca, A., del Hoyo, L., Rodríguez, J., Catuara-Solarz, S., Sánchez-Gutiérrez, J., Dueñas-Espín, I., Hernández, G., Peña-Casanovas, J., Langohr, K., Videla, S., Blehaut, H., Farré, M., Dierssen, M. A new cognitive evaluation battery for Down syndrome and its relevance for clinical trials. "Frontiers in Psychology", 04 Juny 2015, vol. 6, p. 1-14.
Paraules clau
ALZHEIMERS-DISEASE, DYSFUNCTION, Down syndrome, EXECUTIVE FUNCTION, GENDER-DIFFERENCES, NONDEMENTED ADULTS, QUALITY-OF-LIFE, TESDAD neurocognitive battery, VOXEL-BASED MORPHOMETRY, WILLIAMS-SYNDROME, WORKING-MEMORY, YOUNG-ADULTS, clinical trials as topic, cognition, intellectual disabilities
Grup de recerca
GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica

Participants

  • de Sola Llopis, Susana  (autor)
  • De la Torre Fornell, Rafael  (autor)
  • Sánchez Benavides, Gonzalo  (autor)
  • Benejam, Bessy  (autor)
  • Cuenca, Aída  (autor)
  • del Hoyo, Laura  (autor)
  • Rodríguez, Joan  (autor)
  • Catuara-Solarz, Silvina  (autor)
  • Sánchez-Gutiérrez, Judit  (autor)
  • Dueñas-Espín, Ivan  (autor)
  • Hernández, Gimena  (autor)
  • Peña Casanovas, Jordi  (autor)
  • Langohr, Klaus  (autor)
  • Videla, Sebastià  (autor)
  • Blehaut, Henri  (autor)
  • Farré, Magí  (autor)
  • Dierssen, Mara  (autor)

Arxius