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Cellobiose dehydrogenase functionalized urinary catheter as novel antibiofilm system

Autor
Thallinger, B.; Brandauer, M.; Burger, P.; Sygmund, C.; Ludwig, R.; Ivanova, K.; Kun, J.; Scaini, D.; Burnet, M.; Tzanov, T.; Nyanhongo, G.; Gübitz, G. M,.
Tipus d'activitat
Article en revista
Revista
Journal of biomedical materials research
Data de publicació
2016-10-01
Volum
104
Número
7
Pàgina inicial
1448
Pàgina final
1456
DOI
https://doi.org/10.1002/jbm.b.33491 Obrir en finestra nova
URL
http://onlinelibrary.wiley.com/doi/10.1002/jbm.b.33491/abstract;jsessionid=3BD1EE93FC51A9E28BF37C7DCE22936B.f03t03?systemMessage=Wiley+Online+Library+will+be+unavailable+on+Saturday+5th+December+from+10%3A00-14%3A00+GMT+%2F+05%3A00-09%3A00+EST+%2F+18%3A00-22%3A00+SGT+for+essential+maintenance.+Apologies+for+the+inconvenience. Obrir en finestra nova
Resum
Urinary catheters expose patients to a high risk of acquiring nosocomial infections. To prevent this risk of infection, cellobiose dehydrogenase (CDH), an antimicrobial enzyme able to use various oligosaccharides as electron donors to produce hydrogen peroxide using oxygen as an electron acceptor, was covalently grafted onto plasma-activated urinary polydimethylsiloxane (PDMS) catheter surfaces. Successful immobilization of CDH on PDMS was confirmed by Fourier transformed-infrared spectrometry a...
Paraules clau
Cellobiose Dehydrogenase, Polydimethylsiloxane, Urinary Catheters, Covalent Immobilization, Biocompatibility, Antimicrobial Effect
Grup de recerca
GBMI - Grup de Biotecnologia Molecular i Industrial

Participants

  • Thallinger, Barbara  (autor)
  • Brandauer, Martin  (autor)
  • Burger, Peter  (autor)
  • Sygmund, Christoph  (autor)
  • Ludwig, Roland  (autor)
  • Ivanova, Kristina Dimitrova  (autor)
  • Kun, Jutta  (autor)
  • Scaini, Denis  (autor)
  • Burnet, Michael  (autor)
  • Tzanov, Tzanko  (autor)
  • Nyanhongo, Gibson S.  (autor)
  • Gübitz, Georg M.  (autor)