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Comparison of two different strategies of treatment with zoledronate in HIV-infected patients with low bone mineral density: single dose versus two doses in 2 yearseral density: single dose versus two doses in 2 years

Autor
Negredo, E.; Bonjoch, A.; Perez, N.; Ornelas, A.; Puig, J.; Herrero, C.; Estany, C.; del Rio, L.; Di Gregorio, S.; Echeverria, P.; Clotet, B.
Tipus d'activitat
Article en revista
Revista
HIV medicine
Data de publicació
2015-08-01
Volum
16
Número
7
Pàgina inicial
441
Pàgina final
448
DOI
https://doi.org/10.1111/hiv.12260 Obrir en finestra nova
URL
http://onlinelibrary.wiley.com/doi/10.1111/hiv.12260/full Obrir en finestra nova
Resum
Objectives: Given the need for easily managed treatment of osteoporosis in HIV-infected patients, we evaluated the efficacy and tolerability of two doses of zoledronate, by comparing three groups of patients: those with annual administration, those with biennial administration (one dose in 2 years) and a control group with no administration of zoledronate.; MethodsWe randomized (2:1) 31 patients on antiretroviral therapy with low bone mineral density (BMD) to zoledronate (5mg administered intrav...
Paraules clau
HIV, acid, alendronate, annual administration, antiretroviral therapy, biennial administration, bisphosphonate, bone mineral density, clinical fractures, dual-energy X-ray absorptiometry scan, high prevalence, osteopenia, osteopenia/osteoporosis, osteoporosis, postmenopausal osteoporosis, risk, vitamin-d, zoledronate
Grup de recerca
GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica

Participants

  • Negredo Puigmal, Eugènia  (autor)
  • Bonjoch Badia, Anna  (autor)
  • Perez Alvarez, Nuria  (autor)
  • Ornelas Vargas, Arelly  (autor)
  • Puig, Jordi  (autor)
  • Herrero, C.  (autor)
  • Estany Quera, Carla  (autor)
  • del Rio, Luis  (autor)
  • Di Gregorio, Silvana  (autor)
  • Echeverria Liras, Patricia  (autor)
  • Clotet Sala, Bonaventura  (autor)