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Electrospun scaffolds of polylactide with a different enantiomeric content and loaded with anti-inflammatory and antibacterial drugs

Autor
Llorens, E.; del Valle, LJ.; Puiggali, J.
Tipus d'activitat
Article en revista
Revista
Macromolecular research
Data de publicació
2015-07-01
Volum
23
Número
7
Pàgina inicial
636
Pàgina final
648
DOI
https://doi.org/10.1007/s13233-015-3082-5 Obrir en finestra nova
Projecte finançador
Nuevos polímeros derivados de lactida: estructura, aplicaciones biomédicas y microprocesado.
Repositori
http://hdl.handle.net/2117/103940 Obrir en finestra nova
URL
http://link.springer.com/article/10.1007%2Fs13233-015-3082-5 Obrir en finestra nova
Resum
Polylactide (PLA) electrospun microfibers were prepared and loaded with triclosan (TCS), ketoprofen (KTP), or their combination to obtain multifunctional scaffolds with bactericide and anti-inflammatory properties. Continuous and porous fibers with diameters in the micrometer scale and a unimodal distribution were successfully attained using a dual-electrospinning technique. Dual drug-loaded scaffolds showed a peculiar release that was in contrast to the single drug-loaded systems, which suggest...
Citació
Llorens, E., del Valle, LJ., Puiggali, J. Electrospun scaffolds of polylactide with a different enantiomeric content and loaded with anti-inflammatory and antibacterial drugs. "Macromolecular research", 1 Juliol 2015, vol. 23, núm. 7, p. 636-648.
Paraules clau
bactericide, behavior, biomaterials, crystallization, dual drug-release, electrospinning, fibers, ketoprofen, nanofibers, nanoparticles, packaging materials, poly(l-lactide), poly(lactic acid), polylactide, release, triclosan
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.

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