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Neurophysiological evidence of compensatory brain mechanisms in early-stage multiple sclerosis

Autor
Lopez, M.; Escartín, J.A.; Martinez, S.; Fernandez, R.; Querol, L.; Romero, S.; Mañanas, M.A.; Riba, J.
Tipus d'activitat
Article en revista
Revista
PLoS one
Data de publicació
2015-08-31
Volum
10
Número
8
DOI
https://doi.org/10.1371/journal.pone.0136786 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/78209 Obrir en finestra nova
Resum
Multiple sclerosis (MS) is a chronic central nervous system disorder characterized by white matter inflammation, demyelination and neurodegeneration. Although cognitive dysfunction is a common manifestation, it may go unnoticed in recently-diagnosed patients. Prior studies suggest MS patients develop compensatory mechanisms potentially involving enhanced performance monitoring. Here we assessed the performance monitoring system in early-stage MS patients using the error-related negativity (ERN),...
Citació
Lopez, M., Escartín, J.A., Martinez, S., Fernandez, R., Querol, L., Romero, S., Mañanas, M.A., Riba, J. Neurophysiological evidence of compensatory brain mechanisms in early-stage multiple sclerosis. "PLoS one", 31 Agost 2015, vol. 10, núm. 8.
Paraules clau
Clinically Isolated Syndromes, Event-related Potentials, Error-related Negativity, Cognitive Dysfunction, Attention System, Ms Patients, Impairment, Performance, Activation, Disability
Grup de recerca
BIOART - Anàlisi de Biosenyals per a la Rehabilitació i la Teràpia
CREB - Centre de Recerca en Enginyeria Biomedica

Participants