Carregant...
Carregant...

Vés al contingut (premeu Retorn)

Development of tailored and self-mineralizing citric acid-crosslinked hydrogels for in situ bone regeneration

Autor
Sanchez, A.; Mata, Á.; Mateos, M.; Rodriguez-Cabello , J.C.; Alonso, M.; Planell, J. A.; Engel, E.
Tipus d'activitat
Article en revista
Revista
Biomaterials
Data de publicació
2015-11-01
Volum
68
Pàgina inicial
42
Pàgina final
53
DOI
https://doi.org/10.1016/j.biomaterials.2015.07.062 Obrir en finestra nova
Projecte finançador
EVALUACION BIOLOGICA DE MATERIALS BIOACTIVOS, BIOMIMETICOS Y MULTIFUNCIOINALES PARA REGENERACION OSEA
Repositori
http://hdl.handle.net/2117/87684 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S014296121500650X Obrir en finestra nova
Resum
Bone tissue engineering demands alternatives overcoming the limitations of traditional approaches in the context of a constantly aging global population. In the present study, elastin-like recombinamers hydrogels were produced by means of carbodiimide-catalyzed crosslinking with citric acid, a molecule suggested to be essential for bone nanostructure. By systematically studying the effect of the relative abundance of reactive species on gelation and hydrogel properties such as functional groups ...
Citació
Sanchez, A., Mata, Á., Mateos, M., Rodriguez-Cabello , J.C., Alonso, M., Planell, J., Engel, E. Development of tailored and self-mineralizing citric acid-crosslinked hydrogels for in situ bone regeneration. "Biomaterials", 01 Novembre 2015, vol. 68, p. 42-53.
Paraules clau
Biomimetic material, Biomineralisation, Bone tissue engineering, Cross-linking, Hydrogel, Mesenchymal stem cell, adhesion, collagen, differentiation, extracellular-matrix, hydroxyapatite, image-analysis, imulated body-fluid, mechanism, stem-cell fate, tissue
Grup de recerca
CREB - Centre de Recerca en Enginyeria Biomedica
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants

Arxius