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Antibiotic-loaded polypropylene surgical meshes with suitable biological behavior by plasma functionalization and polymerization

Autor
Labay, C.; Canal, J.M.; Modic, M.; Cvelbar, U.; Quiles, M.T.; Armengol, M.; Arbós, M.A.; Gil, F.J.; Canal, C.
Tipus d'activitat
Article en revista
Revista
Biomaterials
Data de publicació
2015-12-01
Volum
71
Pàgina inicial
132
Pàgina final
144
DOI
https://doi.org/10.1016/j.biomaterials.2015.08.023 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/78793 Obrir en finestra nova
Resum
Hernia repair is one of the most common operations in general surgery, and its associated complications typically relate to infections, among others. The loading of antibiotics to surgical meshes to deliver them locally in the abdominal hernia repair site can be one way to manage infections associated with surgical implants. However, the amount of drug loaded is restricted by the low wettability of polypropylene (PP). In this work, plasma has been used to tailor the surface properties of PP mesh...
Citació
Labay, C., Canal, J.M., Modic, M., Cvelbar, U., Quiles, M.T., Armengol, M., Arbós, M.A., Gil, F.J., Canal, C. Antibiotic-loaded polypropylene surgical meshes with suitable biological behavior by plasma functionalization and polymerization. "Biomaterials", 01 Desembre 2015, vol. 71, p. 132-144.
Paraules clau
Abdominal-wall, Antibacterial activity, Biomedical applications, Drug delivery, Fibroblast, In-vitro, Infection, Inguinal-hernia repair, Perfluorinated ionomer, Plasma, Polyamide 6.6, Polypropylene, Protein adsorption, Surface modification, Surgical mesh
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
TECTEX - Grup de Recerca en Tecnologia Tèxtil

Participants