Carregant...
Carregant...

Vés al contingut (premeu Retorn)

Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies

Autor
Rocas, P.; Hoyos-Nogués, M.; Rocas, J.; Manero, J.; Gil, F.J.; Albericio, F.; Mas-Moruno, C.
Tipus d'activitat
Article en revista
Revista
Advanced healthcare materials
Data de publicació
2015
Volum
4
Número
13
Pàgina inicial
1
Pàgina final
5
DOI
https://doi.org/10.1002/adhm.201500245 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/83799 Obrir en finestra nova
URL
http://onlinelibrary.wiley.com/doi/10.1002/adhm.201500245/abstract;jsessionid=2095605E09E4E93BCC7A3EC5BB605551.f02t03 Obrir en finestra nova
Resum
A novel class of polyurethane-polyurea nanoparticles (PUUa NPs) to install multifunctionality on biomaterials is presented. Biofunctionalization of titanium with roxithromycin loaded RGD-decorated PUUa NPs results in an outstanding improvement of osteoblast adhesion and strong suppression of bacterial attachment. This strategy represents a powerful approach to enhance the osseointegration of implant materials.
Citació
Rocas, P., Hoyos, M., Rocas, J., Manero, J., Gil, F.J., Albericio, F., Mas-Moruno, C. Installing multifunctionality on titanium with RGD-decorated polyurethane-polyurea roxithromycin loaded nanoparticles: toward new osseointegrative therapies. "Advanced Healthcare Materials", 2015, vol. 4, núm. 13, p. 1-5.
Paraules clau
RGD peptides, antibacterial properties, multifunctional nanomaterials, surface functionalization, titanium osseointegration
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants