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Customized interface biofunctionalization of decellularized extracellular matrix: towards enhanced endothelialization

Autor
Aubin, H.; Mas-Moruno, C.; Iijima, M.; Schütterle, N.; Steinbrink, M.; Assmann, A.; Gil, F.J.; Lichtenberg, A.; Pegueroles, Marta; Akhyari, P.
Tipus d'activitat
Article en revista
Revista
Tissue engineering. Part C, methods
Data de publicació
2016
Volum
22
Número
5
Pàgina inicial
496
Pàgina final
508
DOI
https://doi.org/10.1089/ten.TEC.2015.0556 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/86560 Obrir en finestra nova
URL
http://online.liebertpub.com/doi/10.1089/ten.tec.2015.0556 Obrir en finestra nova
Resum
Interface biofunctionalization strategies try to enhance and control the interaction between implants and host organism. Decellularized extracellular matrix (dECM) is widely used as a platform for bioengineering of medical implants, having shown its suitability in a variety of preclinical as well as clinical models. In this study, specifically designed, custom-made synthetic peptides were used to functionalize dECM with different cell adhesive sequences (RGD, REDV, and YIGSR). Effects on in vitr...
Citació
Aubin, H., Mas-Moruno, C., Iijima, M., Schütterle, N., Steinbrink, M., Assmann, A., Gil, F.J., Lichtenberg, A., Pegueroles, Marta, Akhyari, P. Customized interface biofunctionalization of decellularized extracellular matrix: towards enhanced endothelialization. "Tissue engineering", 2016, núm. April.
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants