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  • Differential light-induced responses in sectorial inherited retinal degeneration

     Ramon Portés, Eva; Cordomi, Arnau; Aguilà Cerdà, Mònica; Srinivasan, Sundaramoorthy; Dong, Xiaoyun; Moore, A.T.; Webster, A.R.; Cheetham, Michael E; Garriga Sole, Pere
    Journal of biological chemistry
    Vol. 289, num. 52, p. 35918-35928
    DOI: 10.1074/jbc.M114.609958
    Date of publication: 2014-12-26
    Journal article
  • Preferential activation by galanin 1-15 fragment of the GalR1 protomer of a GalR1-GalR2 heteroreceptor complex

     Borroto Escuela, Dasiel Óscar; Narvaez, Manuel; Di Palma, Michael; Calvo, Feliciano; Rodríguez, David; Millón, Carmelo; Carlsson, Jens; Agnati, Luigi F.; Garriga Sole, Pere; Díaz Cabiale, Zaida; Fuxe, Kjell
    Biochemical and biophysical research communications
    Vol. 452, num. 3, p. 347-353
    DOI: 10.1016/j.bbrc.2014.08.061
    Date of publication: 2014-09-26
    Journal article
  • Mercury-induced dark-state instability and photobleaching alterations of the visual G-protein coupled receptor rhodopsin

     Morillo Cazorla, Margarita; Toledo Gonzalez, Darwin; Perez Gonzalez, Juan Jesus; Ramon Portés, Eva; Garriga Sole, Pere
    Chemical research in toxicology
    Vol. 27, num. 7, p. 1219-1226
    DOI: 10.1021/tx500114s
    Date of publication: 2014-07-01
    Journal article
  • Hsp90 inhibition protects against inherited retinal degeneration  Open access

     Aguilà Cerdà, Mònica; Bevilacqua, Dalila; McCulley, Caroline; Schwarz, Nele; Athanasiou, Dimitra; Kanuga, Naheed; Novoselov, Sergey S.; Lange, Clemens A.K.; Ali, Robin R.; Bainbridge, James W.; Gias, Carlos; Coffey, Peter J.; Garriga Sole, Pere; Cheetham, Michael E
    Human molecular genetics
    Vol. 23, num. 8, p. 2164-2175
    DOI: 10.1093/hmg/ddt613
    Date of publication: 2014-04-15
    Journal article
    Access to the full text
  • Binding specificity of retinal analogs to photoactivated visual pigments suggest mechanism for fine-tuning GPCR-ligand interactions

     Srinivasan, Sundaramoorthy; Ramon Portés, Eva; Cordomi, Arnau; Garriga Sole, Pere
    Chemistry and biology
    Vol. 21, num. 3, p. 369-378
    DOI: 10.1016/j.chembiol.2014.01.006
    Date of publication: 2014-03-20
    Journal article
  • FUNCTIONAL MATERIALS FOR LAST DIAGNOSIS OF WOUND INFECTION

     Morillo Cazorla, Margarita; Garriga Sole, Pere; Miralles Lluma, Rosa; Tzanov, Tzanko
    Competitive project
  • G-protein-coupled receptors oligomerization: emerging signaling units and new opportunities for drug design

     Tena Campos, Merce; Ramon Portés, Eva; Rivera Rodriguez, Diana Marcela; Borroto Escuela, Dasiel Óscar; Romero Fernández, Wilber; Fuxe, Kjell; Garriga Sole, Pere
    Current protein and peptide science
    Vol. 15, num. 7, p. 648-658
    DOI: 10.2174/1389203715666140901094248
    Date of publication: 2014-01-01
    Journal article
  • Differential uptake and release kinetics of photoactivated rhodopsin and red cone opsin

     Srinivasan, Sundaramoorthy; Ramon Portés, Eva; Morillo Cazorla, Margarita; Garriga Sole, Pere
    Congreso de la Sociedad Española de Bioquímica y Biología Molecular
    Presentation's date: 2013-09-04
    Presentation of work at congresses
  • GalR1 interactions with 5HT1A, galanin and its N(1-15) terminal fragment

     Tena Campos, Merce; Borroto Escuela, Dasiel Óscar; Romero Fernández, Wilber; Rivera Rodriguez, Diana Marcela; Lupala Lupala, Cecylia Severin; Perez Gonzalez, Juan Jesus; Fuxe, Kjell; Garriga Sole, Pere
    Congreso de la Sociedad Española de Bioquímica y Biología Molecular
    Presentation's date: 2013-09-04
    Presentation of work at congresses
  • Molecular insights into sector retinitis pigmentosa retinal disease

     Ramon Portés, Eva; Toledo Gonzalez, Darwin; Aguilà Cerdà, Mònica; Moore, A.T.; Webster, A.R.; Cheetham, Michael E; Garriga Sole, Pere
    International Union of Biochemistry and Molecular Biology Congress
    p. 429-
    Presentation's date: 2013-09-04
    Presentation of work at congresses
  • Point mutations in visual photoreceptors: new insights into rhodopsin photoactivation

     Garriga Sole, Pere
    European Meeting on Phototransduction
    Presentation's date: 2013-06-20
    Presentation of work at congresses
  • Improved Conformational Stability of the Visual G Protein-Coupled Receptor Rhodopsin by Specific Interaction with Docosahexaenoic Acid Phospholipid

     Sanchez Martin, Maria Jesús; Ramon Portés, Eva; Torrent Burgues, Juan; Garriga Sole, Pere
    Chembiochem
    Vol. 14, num. 5, p. 639-644
    DOI: 10.1002/cbic.201200687
    Date of publication: 2013-03
    Journal article
  • G protein-coupled receptor heterodimerization in the brain

     Borroto Escuela, Dasiel Óscar; Romero Fernández, Wilber; Garriga Sole, Pere; Ciruela, Francisco; Narvaez, Manuel; Tarakanov, O.V.; Palkovits, Miklós; Agnati, Luigi F.; Fuxe, Kjell
    Methods in enzymology
    Vol. 521, p. 281-294
    DOI: 10.1016/B978-0-12-391862-8.00015-6
    Date of publication: 2013
    Journal article
  • Fluorescence studies of DHA liposomes ability to stabilize the G-protein-coupled receptor rhodopsin

     Sánchez Martín, Maria Jesús; Ramon Portés, Eva; Garriga Sole, Pere
    Luminescence
    Vol. 27, p. 551-552
    DOI: 10.1002/bio.2432
    Date of publication: 2012-12-19
    Journal article
  • On the existence and function of galanin receptor heteromers in the central nervous system

     Fuxe, Kjell; Borroto Escuela, Dasiel Óscar; Romero Fernández, Wilber; Tarakanov, O.V.; Calvo, Feliciano; Garriga Sole, Pere; Tena Campos, Merce; Narvaez, Manuel; Millón, Carmelo; Parrado, Concepción; Ciruela, Francisco; Agnati, Luigi F.; Narvaez, José Antonio; Díaz Cabiale, Zaida
    Frontiers in Endocrinology
    Vol. 3, num. 127, p. 1-12
    DOI: 10.3389/fendo.2012.00127
    Date of publication: 2012-10-26
    Journal article
  • Cone opsin regeneration by retinal analogs

     Ramon Portés, Eva; Srinivasan, Sundaramoorthy; Sánchez Martín, Maria Jesús; Garriga Sole, Pere
    International Conference on Retinal Proteins
    Presentation's date: 2012-10-02
    Presentation of work at congresses
  • Visual phototransduction: from visual pigments mutations to retinal disease

     Ramon Portés, Eva; Garriga Sole, Pere
    European Meeting on Phototransduction
    Presentation's date: 2012-09-29
    Presentation of work at congresses
  • Improving the stability of the visual G-protein-coupled receptor rhodopsin in DHA liposomes

     Sánchez Martín, Maria Jesús; Ramon Portés, Eva; Garriga Sole, Pere
    International Union of Biochemistry and Molecular Biology Congress
    p. 471-
    Presentation's date: 2012-09-05
    Presentation of work at congresses
  • Improving the stability of the visual G-protein-coupled receptor rhodopsin in DHA liposomes

     Sanchez Martin, Maria Jesús; Ramon Portés, Eva; Garriga Sole, Pere
    The FEBS journal
    Vol. 279, num. SI., p. 471
    Date of publication: 2012-09
    Journal article
  • Ajut Fundación Ramon Areces

     Ramon Portés, Eva; Urtubia Vicario, Cesar; Perez Gonzalez, Juan Jesus; Torrent Burgues, Juan; Morillo Cazorla, Margarita; Garriga Sole, Pere
    Competitive project
  • Extrasynaptic neurotransmission in the modulation of brain function. Focus on the striatal neuronal-glial networks

     Fuxe, Kjell; Borroto Escuela, Dasiel Óscar; Romero Fernández, Wilber; Díaz Cabiale, Zaida; Rivera, Alicia; Ferraro, L.; Tanganelli, S.; Tarakanov, O.V.; Garriga Sole, Pere; Narvaez, Manuel; Ciruela, Francisco; Guescini, M.; Agnati, Luigi F.
    Frontiers in Physiology
    Vol. 3, num. 136
    DOI: 10.3389/fphys.2012.00136
    Date of publication: 2012-06
    Journal article
  • Fluorescence studies of DHA liposomesability to stabilize the activeconformation of rhodopsin

     Sánchez Martín, Maria Jesús; Ramon Portés, Eva; Garriga Sole, Pere
    International Symposium on Luminiscence Spectrometry
    p. 17
    Presentation's date: 2012-05-02
    Presentation of work at congresses
  • ADDED VALUE FROM HIGH PROTEIN AND HIGH OIL INDUSTRIAL CO-STREAMS

     Torrent Burgues, Juan; Morillo Cazorla, Margarita; Macedo Fernandes, Margarida Maria; Garriga Sole, Pere; Rivera Rodriguez, Diana Marcela; Tzanov, Tzanko
    Competitive project
  • NOVEL APPROACHES FOR PREVENTION AND DEGENERATION OF PATHOGENIC BACTERIA BIOFILMS FORMED ON MEDICAL DEVICES E.G.CATHETERS

     Ivanova, Kristina Dimitrova; Diaz Blanco, Carlos; Morillo Cazorla, Margarita; Torrent Burgues, Juan; Macedo Fernandes, Margarida Maria; Garriga Sole, Pere; Tzanov, Tzanko
    Competitive project
  • ALTERACIONES PROCESOS ACTIVACION Y TRANSDUCCION DE SEÑAL DE RECEPTORES ACOPLADOS A PROTEINAS G

     Torrent Burgues, Juan; Hoyo Perez, Javier; Ramon Portés, Eva; Gotzens Garcia, Guadalupe; Guaus Guerrero, Ester; Morillo Cazorla, Margarita; Urtubia Vicario, Cesar; Roset Calzada, M. Lourdes; Garriga Sole, Pere
    Competitive project
  • Comparative study of rhodopsin

     Srinivasan, Sundaramoorthy; Ramon Portés, Eva; Garriga Sole, Pere
    International Congress of the Spanish Biophysical Society
    Presentation of work at congresses
  • Molecular modeling of the M3 acetylcholine muscarinic receptor and its binding site

     Martinez Archundia, Marlet; Cordomí Montoya, Arnau; Garriga Sole, Pere; Perez Gonzalez, Juan Jesus
    Journal of biomedicine and biotechnology
    Vol. 2012, num. 789741
    DOI: 10.1155/2012/789741
    Date of publication: 2012
    Journal article
  • In vitro influence of Hg(II) on rhodopsin structure and function

     Morillo Cazorla, Margarita; Toledo Gonzalez, Darwin; Ramon Portés, Eva; Garriga Sole, Pere
    International Congress of the Spanish Biophysical Society
    p. 66-
    Presentation's date: 2012
    Presentation of work at congresses
  • Salt effects on the conformational stability of the visual G-protein-coupled receptor rhodopsin

     Reyes Alcaraz, Arfaxad; Martinez Archundia, Marlet; Ramon Portés, Eva; Garriga Sole, Pere
    Biophysical journal
    Vol. 101, num. 11, p. 2798-2806
    DOI: 10.1016/j.bpj.2011.09.049
    Date of publication: 2011-12-07
    Journal article
  • Altered trafficking and unfolded protein response induction as a result of M3 muscarinic receptor impaired N-glycosylation

     Romero Fernández, Wilber; Borroto Escuela, Dasiel Óscar; Pérez Alea, Miliedys; García Mesa, Yoelvis; Garriga Sole, Pere
    Glycobiology
    Vol. 21, num. 12, p. 1663-1672
    DOI: 10.1093/glycob/cwr105
    Date of publication: 2011-12
    Journal article
  • Molecular mechanisms of disease for mutations at Gly-90 in rhodopsin

     Toledo Gonzalez, Darwin; Ramon Portés, Eva; Aguilà Cerdà, Mònica; Cordomí Montoya, Arnau; Perez Gonzalez, Juan Jesus; Mendes, H.F.; Cheetham, Michael E; Garriga Sole, Pere
    Journal of biological chemistry
    Vol. 286, num. 46, p. 39993-40001
    DOI: 10.1074/jbc.M110.201517
    Date of publication: 2011-11-18
    Journal article
  • La química i la societat

     Grau Vilalta, Maria Dolors; Font Soldevila, Jose; Sanz Balague, Joaquim; Guaus Guerrero, Ester; Calvet Tarragona, Aurelio; Salán Ballesteros, Mª Núria; Martínez Martínez, María R.; Farran Marsa, Adriana; Gorchs Altarriba, Roser; Alvarez Del Castillo, M. Dolores; Garrido Soriano, Nuria; Morillo Cazorla, Margarita; Almajano Pablos, Maria Pilar; Cardona Planes, Anna Maria; Macanás de Benito, Jorge; Bonsfills Pedros, Ana; Gamisans Noguera, Javier; Dorado Castaño, Antonio David; Lao Luque, Concepcion; Torrent Burgues, Juan; Molins Duran, Gemma; Colom Fajula, Xavier; Carrillo Navarrete, Fernando; Ramon Portés, Eva; Garriga Sole, Pere; Sole Sardans, M. Montserrat; Ardanuy Raso, Monica; Pares Sabates, Ferran; Roncero Vivero, Maria Blanca; Cusola Aumedes, Oriol
    Collaboration in exhibitions
  • Differential expression of muscarinic acetylcholine receptor subtypes in Jurkat cells and their signaling

     Alea, M.P.; Borroto Escuela, Dasiel Óscar; Romero Fernández, Wilber; Fuxe, Kjell; Garriga Sole, Pere
    Journal of neuroimmunology
    Vol. 237, num. 1-2, p. 13-22
    DOI: 10.1016/j.jneuroim.2011.05.010
    Date of publication: 2011-08-15
    Journal article
  • Structural and Stability Studies of Class A G-protein coupled receptors

     Reyes Alcaraz, Arfaxad
    Department of Chemical Engineering, Universitat Politècnica de Catalunya
    Theses
  • Photointermediate stability changes in rhodopsin mutants associated with retinitis pigmentosa

     Ramon Portés, Eva; Bosch Presegue, Laia; Toledo Gonzalez, Darwin; Cordomí Montoya, Arnau; Garriga Sole, Pere
    Congreso de la Sociedad de Biofísica de España
    p. 140
    Presentation's date: 2011-07-01
    Presentation of work at congresses
  • Overproduction of human M3 muscarinic acetylcholine receptor: An approach toward structural studies

     Romero Fernández, Wilber; Garriga Sole, Pere; Borroto Escuela, Dasiel Óscar
    Biotechnology progress
    Vol. 27, num. 3, p. 838-845
    DOI: 10.1002/btpr.615
    Date of publication: 2011-06
    Journal article
  • Alterations in the photoactivation pathway of rhodopsin mutants associated with retinitis pigmentosa

     Bosch Presegue, Laia; Ramon Portés, Eva; Toledo Gonzalez, Darwin; Cordomi Montoya, Arnau; Garriga Sole, Pere
    The FEBS journal
    Vol. 278, num. 9, p. 1493-1505
    DOI: 10.1111/j.1742-4658.2011.08066.x
    Date of publication: 2011-05
    Journal article
  • Study of the M3 muscarinic acetylcholine receptor by molecular dynamics simulations and site-directed mutagenesis

     Martínez Archundia, Marlet Themis
    Department of Chemical Engineering, Universitat Politècnica de Catalunya
    Theses
  • Muscarinic receptor family interacting proteins: Role in receptor function

     Borroto Escuela, Dasiel Óscar; Correia, Patricia A.; Romero Fernández, Wilber; Narvaez, Manuel; Fuxe, Kjell; Ciruela, Francisco; Garriga Sole, Pere
    Journal of neuroscience methods
    Vol. 195, num. 2, p. 161-169
    DOI: 10.1016/j.jneumeth.2010.11.025
    Date of publication: 2011-02-15
    Journal article
  • Hydrophobic amino acids at the cytoplasmic ends of helices 3 and 6 of rhodopsin conjointly modulate transducin activation

     Bosch Presegue, Laia; Iarriccio, Laura; Aguilà Cerdà, Mònica; Toledo Gonzalez, Darwin; Ramon Portés, Eva; Cordomí Montoya, Arnau; Garriga Sole, Pere
    Archives of biochemistry and biophysics
    Vol. 506, num. 2, p. 142-149
    DOI: 10.1016/j.abb.2010.11.019
    Date of publication: 2011-02-15
    Journal article
  • Molecular mechanisms for retinal diseases caused by mutations at Gly90 in the visual G protein coupled receptor, rhodopsin

     Ramon Portés, Eva; Toledo Gonzalez, Darwin; Aguilà Cerdà, Mònica; Cordomí Montoya, Arnau; Mendes, Hugo F.; Cheetham, Michael E; Garriga Sole, Pere
    Congreso de la Sociedad Española de Bioquímica y Biología Molecular
    p. 239-240
    Presentation of work at congresses
  • Dissecting the conserved NPxxY motif of the M(3) muscarinic acetylcholine receptor: Critical role of Asp-7.49 for receptor signaling and multiprotein complex formation  Open access

     Borroto Escuela, Dasiel Óscar; Romero Fernández, Wilber; Garcia Negredo, G.; Correia, Patricia A.; Garriga Sole, Pere; Fuxe, Kjell; Ciruela, Francisco
    Cellular physiology and biochemistry
    Vol. 28, num. 5, p. 1009-1022
    DOI: 10.1159/000335788
    Date of publication: 2011
    Journal article
    Access to the full text
  • Efficient G-protein activation by fully-functional rhodopsin in the dark by the release of critical structural constraints

     Ramon Portés, Eva; Toledo Gonzalez, Darwin; Reyes Alcaraz, Arfaxad; Morillo Cazorla, Margarita; Garriga Sole, Pere
    Congreso de la Sociedad Española de Bioquímica y Biología Molecular
    p. 248-
    Presentation of work at congresses
  • Novel insights into galanin Nterminal fragment (1-15)- GalR1/GalR2 heteroreceptor interactions

     Perez Gonzalez, Juan Jesus; Garriga Sole, Pere
    Congreso de la Sociedad Española de Bioquímica y Biología Molecular
    p. 249
    Presentation of work at congresses
  • Conformational Studies of the M3 Acetylcholine Muscarinic Receptor and its Binding Site

     Perez Gonzalez, Juan Jesus; Garriga Sole, Pere
    Congreso de la Sociedad de Biofísica de España
    p. 104
    Presentation of work at congresses
  • Inorganic salt effects on the stability of the active and inactive conformations of the G-protein coupled receptor rhodopsin

     Reyes Alcaraz, Arfaxad; Martinez Archundia, Marlet; Garriga Sole, Pere
    Congreso de la Sociedad de Biofísica de España
    p. 151
    Presentation of work at congresses
  • New insights into the molecular mechanisms of rhodopsin retinitis pigmentosa

     Aguilà Cerdà, Mònica
    Department of Chemical Engineering, Universitat Politècnica de Catalunya
    Theses
  • On-chip photoactivation of heterologously expressed rhodopsin allows kinetic analysis of G-protein signaling by surface plasmon resonance spectroscopy

     Komolov, Konstantin E.; Aguilà Cerdà, Mònica; Toledo Gonzalez, Darwin; Manyosa Ribatallada, Joan; Garriga Sole, Pere; Koch, Karl-Wilhelm
    Analytical and bioanalytical chemistry
    Vol. 397, num. 7, p. 2967-2976
    DOI: 10.1007/s00216-010-3876-4
    Date of publication: 2010-08
    Journal article
  • The M-5 muscarinic acetylcholine receptor third intracellular loop regulates receptor function and oligomerization

     Borroto Escuela, Dasiel Óscar; Garcia Negredo, G.; Garriga Sole, Pere; Fuxe, Kjell; Ciruela, Francisco
    Biochimica et biophysica acta. Molecular cell research
    Vol. 1803, num. 7, p. 813-825
    DOI: 10.1016/j.bbamcr.2010.04.002
    Date of publication: 2010-07
    Journal article