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Mutual regulation causes co-entrainment between a synthetic oscillator and the bacterial cell cycle

Autor
Dies, M.; Galera, L.; Garcia, J.
Tipus d'activitat
Article en revista
Revista
Integrative Biology
Data de publicació
2016-01-01
Volum
8
Número
4
Pàgina inicial
533
Pàgina final
541
DOI
https://doi.org/10.1039/c5ib00262a Obrir en finestra nova
Projecte finançador
ESTOCASTICIDAD EN SISTEMAS COMPLEJOS NOLINEALES
Repositori
http://hdl.handle.net/2117/88243 Obrir en finestra nova
Resum
The correct functioning of cells requires the orchestration of multiple cellular processes, many of which are inherently dynamical. The conditions under which these dynamical processes entrain each other remain unclear. Here we use synthetic biology to address this question in the case of concurrent cellular oscillations. Specifically, we study at the single-cell level the interaction between the cell division cycle and a robust synthetic gene oscillator in Escherichia coli. Our results suggest ...
Citació
Dies, M., Galera, L., Garcia, J. Mutual regulation causes co-entrainment between a synthetic oscillator and the bacterial cell cycle. "Integrative Biology", 01 Gener 2016, vol. 8, núm. 4, p. 533-541.
Paraules clau
CLPXP, DNA-replication, circadian clock, degradation machine, division, dynamics, esherichia-coli, gene-expression, initiation, mechanism
Grup de recerca
CEBIM - Centre de Biotecnologia Molecular
DONLL - Dinàmica no Lineal, Òptica no Lineal i Làsers

Participants

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