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Confinement of a ß-barrel protein in nanoperforated free-standing nanomembranes for ion transport

Autor
Puiggali, A.; Pérez-Madrigal, M.M.; del Valle, LJ.; Armelin, E.; Casas, M.; Michaux, Catherine Anne Gisèle; Perpète, Eric A.; Estrany, F.; Aleman, C.
Tipus d'activitat
Article en revista
Revista
Nanoscale
Data de publicació
2016-10-14
Volum
8
Número
38
Pàgina inicial
16922
Pàgina final
16935
DOI
https://doi.org/10.1039/c6nr04948f Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/91323 Obrir en finestra nova
URL
http://pubs.rsc.org/en/Content/ArticleLanding/2016/NR/C6NR04948F#!divAbstract Obrir en finestra nova
Resum
Bioinspired free-standing nanomembranes (FSNMs) for selective ion transport have been tailored by immobilizing the Omp2a ß-barrel membrane protein inside nanoperforations created in flexible poly(lactic acid) (PLA) nanomembranes. Perforated PLA FSNMs have been prepared by spin-coating a 99 : 1 PLA : poly(vinyl alcohol) mixture, and through a phase segregation process nanofeatures with dimensions similar to the entire nanomembrane thickness (~110 nm) were induced. These nanofeatures have subsequ...
Citació
Puiggali, A., Pérez-Madrigal, M.M., del Valle, LJ., Armelin, E., Casas, M., Michaux, C., Perpete, E., Estrany, F., Aleman, C. Confinement of a ß-barrel protein in nanoperforated free-standing nanomembranes for ion transport. "Nanoscale", 14 Octubre 2016, vol. 8, núm. 38, p. 16922-16935.
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies
PSEP - Polimers Sintètics: Estructura i Propietats. Polimers Biodegradables.

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