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Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation

Autor
Castellanos, M.; Mas-Moruno, C.; Grau, A.; Serra-Picamal, X.; Trepat, Xavier; Albericio, F.; Joner, M.; Gil, F.J.; Ginebra, M.P.; Manero, J.; Pegueroles, Marta
Tipus d'activitat
Article en revista
Revista
Applied surface science
Data de publicació
2017-01-30
Volum
393
Pàgina inicial
82
Pàgina final
92
DOI
https://doi.org/10.1016/j.apsusc.2016.09.107 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/102106 Obrir en finestra nova
URL
http://www.sciencedirect.com/science/article/pii/S0169433216319857 Obrir en finestra nova
Resum
Biomimetic surface modification with peptides that have specific cell-binding moieties is a promising approach to improve endothelialization of metal-based stents. In this study, we functionalized CoCr surfaces with RGDS, REDV, YIGSR peptides and their combinations to promote endothelial cells (ECs) adhesion and proliferation. An extensive characterization of the functionalized surfaces was performed by XPS analysis, surface charge and quartz crystal microbalance with dissipation monitoring (QCM...
Citació
Castellanos, M., Mas-Moruno, C., Grau, A., Serra-Picamal, X., Trepat, Xavier, Albericio, F., Joner, M., Gil, J., Ginebra, M.P., Manero, J., Pegueroles, M. Functionalization of CoCr surfaces with cell adhesive peptides to promote HUVECs adhesion and proliferation. "Applied surface science", 30 Gener 2017, vol. 393, p. 82-92.
Paraules clau
Cell adhesive peptides, CoCr alloy, Endothelialization, HUVEC proliferation, SMCs adhesion, Surface functionalization
Grup de recerca
BBT - Biomaterials, Biomecànica i Enginyeria de Teixits
CREB - Centre de Recerca en Enginyeria Biomedica
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona

Participants