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Validation of semi-quantitative methods for DAT SPECT: influence of anatomical variability and partial volume effect

Autor
Gallego, J.; Niñerola-Baizán, A.; Cot, A.; Sempau, J.
Tipus d'activitat
Article en revista
Revista
Physics in medicine and biology
Data de publicació
2015
Volum
60
Número
15
Pàgina inicial
5925
Pàgina final
5938
DOI
https://doi.org/10.1088/0031-9155/60/15/5925 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/99276 Obrir en finestra nova
Resum
The aim of this work was to evaluate the influence of anatomical variability between subjects and of the partial volume effect (PVE) on the standardized Specific Uptake Ratio (SUR) in [123I]FP-bib SPECT studies. To this end, magnetic resonance (MR) images of 23 subjects with differences in the striatal volume of up to 44% were segmented and used to generate a database of 138 Monte Carlo simulated SPECT studies. Data included normal uptakes and pathological cases. Studies were reconstructed by fi...
Citació
Gallego, J., Niñerola-Baizán, A., Cot, A., Sempau, J. Validation of semi-quantitative methods for DAT SPECT: influence of anatomical variability and partial volume effect. "Physics in medicine and biology", 2015, vol. 60, núm. 15, p. 5925-5938.
Grup de recerca
CREB - Centre de Recerca en Enginyeria Biomedica
DRM - Dosimetria i Radiofísica Mèdica

Participants

  • Gallego, J.  (autor)
  • Niñerola-Baizán, A.  (autor)
  • Cot, A.  (autor)
  • Sempau Roma, Josep  (autor)