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Reentry and ectopic pacemakers emerge in a three-dimensional model for a slab of cardiac tissue with diffuse microfibrosis near the percolation threshold

Autor
Alonso, S.; Weber, R.; Bär, M.
Tipus d'activitat
Article en revista
Revista
PLoS one
Data de publicació
2016-11-22
Volum
11
Número
11
Pàgina inicial
1
Pàgina final
23
DOI
https://doi.org/10.1371/journal.pone.0166972 Obrir en finestra nova
Projecte finançador
Ajut per a contractació RYC-2012-11265
Repositori
http://hdl.handle.net/2117/99721 Obrir en finestra nova
URL
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0166972 Obrir en finestra nova
Resum
Arrhythmias in cardiac tissue are generally associated with irregular electrical wave propagation in the heart. Cardiac tissue is formed by a discrete cell network, which is often heterogeneous. Recently, it was shown in simulations of two-dimensional (2D) discrete models of cardiac tissue that a wave crossing a fibrotic, heterogeneous region may produce reentry and transient or persistent ectopic activity provided the fraction of conducting connections is just above the percolation threshold. H...
Citació
Alonso, S., Weber, R., Bär, M. Reentry and ectopic pacemakers emerge in a three-dimensional model for a slab of cardiac tissue with diffuse microfibrosis near the percolation threshold. "PLoS one", 22 Novembre 2016, vol. 11, núm. 11, p. 1-23.
Grup de recerca
BIOCOM-SC - Grup de Biologia Computacional i Sistemes Complexos

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