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Surviving evolutionary escape on complex genotype–phenotype networks

Autor
Ibáñez-Marcelo, E.; Alarcon, T.
Tipus d'activitat
Article en revista
Revista
Journal of mathematical biology
Data de publicació
2016-02
Volum
72
Número
3
Pàgina inicial
623
Pàgina final
647
DOI
https://doi.org/10.1007/s00285-015-0896-x Obrir en finestra nova
URL
http://link.springer.com/article/10.1007%2Fs00285-015-0896-x Obrir en finestra nova
Resum
We study the problem of evolutionary escape and survival of cell populations with a genotype–phenotype structure. We refer to evolutionary escape as the process where a cell of a given ill-adapted population to reach a well-adapted phenotype. Similarly, survival refers to the dynamics of the population once the escape phenotype has been reached. The aim of this paper is to analyse the influence of topological properties associated to robustness and evolvability on the probability of escape and...
Paraules clau
Evolutionary escape, Genotype–phenotype map, Local weighted clustering, Survival probability

Participants

  • Ibáñez Marcelo, Esther  (autor)
  • Alarcon, Tomas  (autor)