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Mathematical modeling of collagen turnover in biological tissue

Autor
Saez, P.; Peña, E.; Martínez, M.A.; Kuhl, E.
Tipus d'activitat
Article en revista
Revista
Journal of mathematical biology
Data de publicació
2012
Volum
67
Número
6
Pàgina inicial
1765
Pàgina final
1793
DOI
https://doi.org/10.1007/s00285-012-0613-y Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/103423 Obrir en finestra nova
URL
http://link.springer.com/article/10.1007/s00285-012-0613-y Obrir en finestra nova
Resum
The final publication is available at Springer via http://dx.doi.org/10.1007/s00285-012-0613-y We present a theoretical and computational model for collagen turnover in soft biological tissues. Driven by alterations in the mechanical environment, collagen fiber bundles may undergo important chronic changes, characterized primarily by alterations in collagen synthesis and degradation rates. In particular, hypertension triggers an increase in tropocollagen synthesis and a decrease in collagen degr...
Citació
Saez, P., Peña, E., Martínez, M.A., Kuhl, E. Mathematical modeling of collagen turnover in biological tissue. "Journal of mathematical biology", 2012, vol. 67, núm. 6, p. 1765-1793.
Paraules clau
Blood vessels, Collagen, Growth, Hypertension, Remodeling, Turnover
Grup de recerca
LACÀN - Mètodes Numèrics en Ciències Aplicades i Enginyeria

Participants

  • Saez Viñas, Pablo  (autor)
  • Peña, Estefania  (autor)
  • Martínez, Miguel Àngel  (autor)
  • Kuhl, Ellen  (autor)

Arxius