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Pilot, double-blind, randomized, placebo-controlled clinical trial of the supplement food Nyaditum resae (R) in adults with or without latent TB infection: safety and immunogenicity

Autor
Montane, E.; Barriocanal, A.; Arellano, A.; Valderrama, A.; Sanz, Y.; Perez, N.; Cardona, P.; Vilaplana, C.
Tipus d'activitat
Article en revista
Revista
PloS one
Data de publicació
2017-02-09
Volum
12
Número
2
DOI
https://doi.org/10.1371/journal.pone.0171294 Obrir en finestra nova
URL
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0171294 Obrir en finestra nova
Resum
Background. Nyaditum resae® (NR) is a galenic preparation of heat-killed Mycobacterium manresensis, a new species of the fortuitum complex, that is found in drinkable water, and that has demonstrated to protect against the development of active TB in a murine experimental model that develop human-like lesions. Methods. Double-blind, randomized, placebo-controlled Clinical Trial (51 volunteers included). Two different doses of NR and a placebo were tested, the randomization was stratified by ...
Grup de recerca
GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica

Participants

  • Montane, Eva  (autor)
  • Barriocanal, Ana Maria  (autor)
  • Arellano, Ana Lucía  (autor)
  • Valderrama, Angelica  (autor)
  • Sanz, Yolanda  (autor)
  • Perez Alvarez, Nuria  (autor)
  • Cardona, Paula  (autor)
  • Vilaplana, Cristina  (autor)
  • Cardona, Pere-Joan  (autor)