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Clinical trial designs using CompARE. An on-line exploratory tool for investigators

Autor
Gomez, M.; Gomez, G.
Tipus d'activitat
Document cientificotècnic
Data
2017-03
Codi
Report DR 2017/1
Repositori
http://hdl.handle.net/2117/104928 Obrir en finestra nova
Resum
Conclusions from randomized clinical trials (RCT) rely primarily on the primary endpoint (PE) chosen at the design stage of the study. There should generally be only one PE which should be able to provide the most clinically relevant and scientific evidence regarding the potential eficacy of the new treatment. Therefore, it is of utmost importance to select it appropriately. Composite endpoints, consisting of the union of several endpoints, are often used as PE in RCT. Gomez and Lagakos (2013) d...
Citació
Gomez, M., Gomez, G. "Clinical trial designs using CompARE. An on-line exploratory tool for investigators". 2017.
Paraules clau
Asymptotic Relative Efficiency, Compare, Composite Endpoint, Non-proportional Hazards, Sample Size, Web-based Application.
Grup de recerca
GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica

Participants