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Multifunctional hydrogel dressing material for treatment of chronic wound

Autor
Stefanov, I.; Pérez-­Rafael, S.; Tzanov, T.
Tipus d'activitat
Presentació treball a congrés
Nom de l'edició
253rd American Chemical Society, National Meeting & Exposition, Advanced Materials, Technologies, Systems & Processes
Any de l'edició
2017
Data de presentació
2017-04-05
Llibre d'actes
253rd American Chemical Society National Meeting & Exposition : Advanced Materials, Technologies, Systems & Processes, April 2-6, 2017 San Francisco, CA
Resum
One­step enzymatic crosslinking approach was used to synthesize multifunctional hydrogels for chronic wounds from thiolated chitosan and gallic acid. Stable at physiological conditions hydrogels with tunable physicomechanical and functional properties were generated with the aid of the oxidative enzyme laccase. The potential of these hydrogels as wound dressing materials was evaluated in vitro against major factors governing the chronicity in wounds, such as myeloperoxidase (MPO) and matrix met...
Grup de recerca
GBMI - Grup de Biotecnologia Molecular i Industrial

Participants