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Multifunctional enzymatically generated hydrogels for chronic wound application

Autor
Stefanov, I.; Hoyo, J.; Cailloux, J.; Santana, O.; Tzanov, T.
Tipus d'activitat
Article en revista
Revista
Biomacromolecules
Data de publicació
2017-04-19
Volum
18
Número
5
Pàgina inicial
1544
Pàgina final
1555
DOI
https://doi.org/10.1021/acs.biomac.7b00111 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/103739 Obrir en finestra nova
URL
http://pubs.acs.org/doi/abs/10.1021/acs.biomac.7b00111 Obrir en finestra nova
Resum
The healing of chronic wounds requires intensive medical intervention at huge healthcare costs. Dressing materials should consider the multifactorial nature of these wounds comprising deleterious proteolytic and oxidative enzymes and high bacterial load. In this work, multifunctional hydrogels for chronic wound application were produced by enzymatic cross- linking of thiolated chitosan and gallic acid. The hydrogels combine several beneficial to wound healing properties, controlling the matrix m...
Grup de recerca
GBMI - Grup de Biotecnologia Molecular i Industrial
POLY2 - Polyfunctional polymeric materials

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