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Pharmacokinetics in morbid obesity: influence of two bariatric surgery techniques on paracetamol and caffeine metabolism

Autor
Goday, A.; Farré, M.; Rodriguez, J.; Ramon, J.; Perez, C.; Papaseit, E.; Civit, E.; Langohr, K.; Li Carbo, M.; De la Torre, R.
Tipus d'activitat
Article en revista
Revista
Obesity Surgery
Data de publicació
2017-12
Volum
27
Número
12
Pàgina inicial
3194
Pàgina final
3201
DOI
https://doi.org/10.1007/s11695-017-2745-z Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/114078 Obrir en finestra nova
URL
https://link.springer.com/article/10.1007%2Fs11695-017-2745-z Obrir en finestra nova
Resum
The purpose of the study was to study the impact of the two most common bariatric surgery techniques on paracetamol pharmacokinetics (a marker of gastric emptying) and caffeine metabolism (a marker of liver function). In the present prospective study, we studied 24 morbid obese patients before, at 4 weeks, and 6 months after having undergone sleeve gastrectomy (n = 10) or Roux-en-Y gastric bypass (n = 14). For comparative purposes, 28 healthy controls (14 normal weights and 14 overweights) were ...
Citació
Goday, A., Farré, M., Rodriguez, J., Ramon, J., Perez, C., Papaseit, E., Civit, E., Langohr, K., Li Carbo, M., De la Torre, R. Pharmacokinetics in morbid obesity: influence of two bariatric surgery techniques on paracetamol and caffeine metabolism. "Obesity Surgery", 30 Maig 2017, vol. 27, núm. 12, p. 3194-3201.
Paraules clau
Caffeine., Clinical trial, Gastric bypass, Metabolism paracetamol, Morbid obesity, Sleeve gastrectomy
Grup de recerca
GRBIO - Grup de Recerca en Bioestadística i Bioinformàtica

Participants

  • Goday Arno, Albert  (autor)
  • Farré, Magí  (autor)
  • Rodriguez Morato, Jose  (autor)
  • Ramon, Jose M.  (autor)
  • Perez Maña, Clara  (autor)
  • Papaseit, Esther  (autor)
  • Civit, Ester  (autor)
  • Langohr, Klaus  (autor)
  • Li Carbo, Marcel  (autor)
  • De la Torre Fornell, Rafael  (autor)