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MetaShot: an accurate workflow for taxon classification of host-associated microbiome from shotgun metagenomic data

Autor
Fosso, B.; Santamaria, M.; D'Antonio, M.; Lovero, D.; Corrado, G.; Vizza, E.; Passaro, N.; Garbuglia, A.; Capobianchi, M.; Crescenzi, M.; Valiente, G.; Pesole, G.
Tipus d'activitat
Article en revista
Revista
Bioinformatics
Data de publicació
2017-06-01
Volum
33
Número
11
Pàgina inicial
1730
Pàgina final
1732
DOI
https://doi.org/10.1093/bioinformatics/btx036 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/106077 Obrir en finestra nova
URL
https://academic.oup.com/bioinformatics/article-lookup/doi/10.1093/bioinformatics/btx036 Obrir en finestra nova
Resum
Shotgun metagenomics by high-throughput sequencing may allow deep and accurate characterization of host-associated total microbiomes, including bacteria, viruses, protists and fungi. However, the analysis of such sequencing data is still extremely challenging in terms of both overall accuracy and computational efficiency, and current methodologies show substantial variability in misclassification rate and resolution at lower taxonomic ranks or are limited to specific life domains (e.g. only bact...
Grup de recerca
ALBCOM - Algorismia, Bioinformàtica, Complexitat i Mètodes Formals

Participants

  • Fosso, Bruno  (autor)
  • Santamaria, Monica  (autor)
  • D'Antonio, M.  (autor)
  • Lovero, D.  (autor)
  • Corrado, G.  (autor)
  • Vizza, E.  (autor)
  • Passaro, N.  (autor)
  • Garbuglia, A.R.  (autor)
  • Capobianchi, M.R.  (autor)
  • Crescenzi, M.  (autor)
  • Valiente Feruglio, Gabriel Alejandro  (autor)
  • Pesole, Graziano  (autor)