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A bayesian test for Hardy-Weinberg equilibrium of bi-allelic X-chromosomal markers

Autor
Puig, X.; Ginebra, J.; Graffelman, J.
Tipus d'activitat
Article en revista
Revista
Heredity
Data de publicació
2017-07
Número
119
Pàgina inicial
226
Pàgina final
236
DOI
https://doi.org/10.1038/hdy.2017.30 Obrir en finestra nova
Projecte finançador
Grup de recerca en dades composicionals (RGCODA: Research group in compositional data)
Repositori
http://hdl.handle.net/2117/110646 Obrir en finestra nova
URL
http://www.nature.com/hdy/journal/vaop/ncurrent/full/hdy201730a.html?foxtrotcallback=true Obrir en finestra nova
Resum
The X chromosome is a relatively large chromosome, harboring a lot of genetic information. Much of the statistical analysis of X-chromosomal information is complicated by the fact that males only have one copy. Recently, frequentist statistical tests for Hardy–Weinberg equilibrium have been proposed specifically for dealing with markers on the X chromosome. Bayesian test procedures for Hardy–Weinberg equilibrium for the autosomes have been described, but Bayesian work on the X chromosome in ...
Citació
Puig, X., Ginebra, J., Graffelman, J. A bayesian test for Hardy-Weinberg equilibrium of bi-allelic X-chromosomal markers. "Heredity", Juliol 2017, núm. 119, p. 226-236.
Paraules clau
Bayesian model selection, Dirichlet prior, Hardy-Weinberg equilibrium, Inbreeding coeffcient, Posterior distribution, X-chromosome
Grup de recerca
ADBD - Anàlisi de Dades Complexes per a les Decisions Empresarials
COSDA-UPC - COmpositional and Spatial Data Analysis

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