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Genuine antiplasticizing effect of water on a glass-former drug

Autor
Ruiz, G.; Romanini, M.; Hauptmann, A.; Loerting, T.; Shalaev, E.; Tamarit, J. Ll.; Pardo, L.; Macovez, R.
Tipus d'activitat
Article en revista
Revista
Scientific reports
Data de publicació
2017-08-07
Volum
7
Pàgina inicial
1
Pàgina final
8
DOI
https://doi.org/10.1038/s41598-017-07643-5 Obrir en finestra nova
Projecte finançador
Vidrios Orgánicos y Metálicos: Estructura, Dinámica y Estabilidad
Repositori
http://hdl.handle.net/2117/108032 Obrir en finestra nova
URL
https://www.nature.com/articles/s41598-017-07643-5 Obrir en finestra nova
Resum
Water is the most important plasticizer of biological and organic hydrophilic materials, which generally exhibit enhanced mechanical softness and molecular mobility upon hydration. The enhancement of the molecular dynamics upon mixing with water, which in glass-forming systems implies a lower glass transition temperature (T g ), is considered a universal result of hydration. In fact, even in the cases where hydration or humidification of an organic glass-forming sample result in stiffer mechanic...
Citació
Ruiz, G., Romanini, M., Hauptmann, A., Loerting, T., Shalaev, E., Tamarit, J. Ll., Pardo, L., Macovez, R. Genuine antiplasticizing effect of water on a glass-former drug. "Scientific reports", 7 Agost 2017, vol. 7, p. 1-8.
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
GCM - Grup de Caracterització de Materials

Participants

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