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Intramolecular backbone center dot center dot center dot backbone hydrogen bonds in polypeptide conformations. The other way around: epsilon-turn

Autor
Toniolo, C.; Crisma, M.; Formaggio, F.; Aleman, C.; Ramakrishnan, C.; Kalmanar, N.; Balaram, P.
Tipus d'activitat
Article en revista
Revista
Biopolymers
Data de publicació
2017-01-01
Volum
108
Número
1
DOI
https://doi.org/10.1002/bip.22911 Obrir en finestra nova
Repositori
http://hdl.handle.net/2117/108922 Obrir en finestra nova
URL
http://onlinelibrary.wiley.com/doi/10.1002/bip.22911/abstract Obrir en finestra nova
Resum
In this study, we performed a detailed literature survey of the ¿-turn in peptides and proteins. This three-dimensional structural feature is characterized by an eleven-membered pseudo-cycle closed by an intramolecular backbone…backbone H-bond. Interestingly, in this motif the direction of the N-H…O¿=¿C H-bond runs opposite to that of the much more popular and extensively investigated a-, ß-, and ¿-turns. We did not authenticate unequivocally the ¿-turn main-chain reversal topology in ...
Citació
Toniolo, C., Crisma, M., Formaggio, F., Aleman, C., Ramakrishnan, C., Kalmanar, N., Balaram, P. Intramolecular backbone center dot center dot center dot backbone hydrogen bonds in polypeptide conformations. The other way around: epsilon-turn. "Biopolymers", 1 Gener 2017, vol. 108, núm. 1.
Paraules clau
NMR, X-ray diffraction, conformational energy calculations, peptide turns, solution conformation
Grup de recerca
CRnE - Centre de Recerca en Ciència i Enginyeria Multiescala de Barcelona
IMEM-BRT- Innovation in Materials and Molecular Engineering - Biomaterials for Regenerative Therapies

Participants

  • Toniolo, Claudio  (autor)
  • Crisma, Marco  (autor)
  • Formaggio, Fernando  (autor)
  • Aleman Llanso, Carlos Enrique  (autor)
  • Ramakrishnan, Chandrasekharan  (autor)
  • Kalmanar, Neh  (autor)
  • Balaram, Padmanabhan  (autor)